Results 31 to 40 of about 95,258 (181)

Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]

open access: yes, 2003
Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R.   +19 more
core   +2 more sources

Utility of IgG4 immunohistochemistry detection in pemphigus diagnosis

open access: yesSAGE Open Medical Case Reports, 2022
Pemphigus includes a group of blistering autoimmune diseases that affect the skin and mucosa, characterized by the formation of epidermal bullous and the presence of antibodies against binding proteins.
Maricela García-Lechuga   +4 more
doaj   +1 more source

A comparative study of expression of Fc receptors in relation to the autoantibody-mediated immune response and neutrophil elastase expression in autoimmune blistering dermatoses

open access: yesPolish Journal of Pathology, 2017
Here we investigated the cutaneous CD32A and CD89 expression in relation to the neutrophil elastase (NE) expression and serum level of anti-desmoglein 1 and 3 (DSG1/DSG3) IgG in pemphigus, anti-BP180/BP230 IgG in bullous pemphigoid (BP), anti-gliadin ...
Justyna Gornowicz-Porowska   +6 more
doaj   +1 more source

Clinical Patterns, Survival, Comorbidities, and Treatment Regimens in 149 Patients With Pemphigus in Tuscany (Italy): A 12-Year Hospital-Based Study

open access: yesFrontiers in Immunology, 2022
IntroductionPemphigus encompasses a group of muco-cutaneous autoimmune bullous diseases characterized by the loss of adhesion between keratinocytes. The disease is associated with increased morbidity and mortality.Materials and MethodsWe characterized ...
Lavinia Quintarelli   +11 more
doaj   +1 more source

The epidemiology of autoimmune bullous diseases in Sudan between 2000 and 2016.

open access: yesPLoS ONE, 2021
ObjectivesAutoimmune bullous diseases vary in their clinico-epidemiological features and burden across populations. Data about these diseases was lacking in Sudan.
Omayma Siddig   +4 more
doaj   +1 more source

Diseases presenting with vesicular and erosive lesions of oral mucous membranes

open access: yesPrzegląd Dermatologiczny, 2017
Disorders of the oral mucosa are an area of interdisciplinary cooperation involving physicians from a diverse range of medical specialties.
Kamila Ociepa, Agnieszka Żebrowska
doaj   +1 more source

Serological Biomarkers and Their Detection in Autoimmune Bullous Skin Diseases

open access: yesDermatology Practical & Conceptual, 2022
Autoimmune bullous diseases (AIBDs) are a group of skin-related disorders that involve damage to structures maintaining cell-cell adhesion, such as desmosomes and hemidesmosomes.
Ilana Heckler   +3 more
doaj   +1 more source

IgG/IgA pemphigus presenting with mixed clinical features of pemphigus erythematosus and IgA pemphigus

open access: yesDermatologica Sinica, 2019
IgG/IgA pemphigus is a phenotype of atypical pemphigus with variable clinical, histological, and immunological manifestations. We describe a unique case of IgG/IgA pemphigus in a 58-year-old male presenting with mixed features of pemphigus erythematosus and IgA pemphigus.
Chun-Bing Chen   +3 more
openaire   +1 more source

Reassessing Remission in Pemphigus Vulgaris: Beyond Complete Remission Towards Meaningful Disease Control

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Current remission criteria for pemphigus vulgaris rely on binary, lesion‐based endpoints that do not capture immunological status, treatment toxicity, or patient quality of life. We argue for a multidimensional framework incorporating minimal disease activity, validated severity scores, glucocorticoid toxicity indices, and patient‐reported ...
Rhea Ahuja   +2 more
wiley   +1 more source

IgA/IgG Pemphigus: A New Atypical Subset of Pemphigus?

open access: yesActa Dermato-Venereologica, 2006
The classical types of pemphigus are well characterized clinically, histologically and immunologically. The tar-get antigens were found to be desmoglein 1 (Dsg1) for pemphigus foliaceus and Dsg3 for pemphigus vulgaris (1). However, there are atypical cases which could not be classified into either of these types. At present two major atypical forms are
Cezary Kowalewski   +5 more
openaire   +2 more sources

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