Results 71 to 80 of about 23,505 (244)

A Review of the Mechanism of Vascular Endothelial Injury in Immunoglobulin A Vasculitis

Frontiers in Physiology, 2022
Immunoglobulin A (IgA) vasculitis (IgAV), also known as Henoch-Schönlein purpura, is the most common form of childhood vasculitis. It is characterized by cutaneous hemorrhage, resulting from red blood cell leakage into the skin or mucosae, possibly ...
Shanshan Xu, Shanshan Han, Yanlin Dai, Long Wang, Xia Zhang, Ying Ding   +5 more
doaj   +1 more source

Comprehensive αβ T‐Cell Receptor Repertoire Analysis Reveals a Unique CD8+ TCR Landscape in DOCK8‐Deficient Patients

Allergy, EarlyView.
T cell receptor repertoire analysis by high‐throughput immune repertoire RNA‐sequencing in the patients with DOCK8 deficiency. Comprehensive comparisons revealed a restricted TCR repertoire diversity in the patients. Additional assessments showed potential auto‐reactive CD8+ T cell clones in the patients.Abbreviations: DOCK8, dedicator of cytokinesis ...
Ceren Bozkurt, Gökhan Cildir, Umran Aba, Rahmi Kutay Erdogan, Nicholas I Warnock I, Chung Hoow Kok, Asena Pinar Sefer, Sule Haskologlu, Sidem Didar Tekeoglu, Gülşah Merve Kılınç, Canberk Ipsir, Tugba Arikoglu, Aylin Kont Ozhan, Saliha Esenboga, Ahmet Özen, Elif Karakoç‐Aydiner, Sevgi Bilgiç Eltan, Çigdem Aydogmus, Candan Islamoglu, Kübra Baskın, Betul Karaatmaca, Ayse Metin, Deniz Çagdaş, Figen Dogu, Aydan Ikinciogullari, Safa Baris, Baran Erman   +26 more
wiley   +1 more source

Biomarkers of IgA vasculitis nephritis in children

PLOS ONE, 2017
Henoch-Schönlein purpura is a systemic vasculitis characterized by IgA deposits, which target the skin, joints, and kidneys, among other organs. In children, prognosis is often good but little is known about biomarkers of pediatric nephritis. We hypothesized that biological markers, including cytokines, immunoglobulins, IgA-immune complexes, IgA ...
Evangeline Pillebout, Agnès Jamin, Hamza Ayari, Pierre Housset, Melissa Pierre, Virginia Sauvaget, Denis Viglietti, Georges Deschenes, Renato C Monteiro, Laureline Berthelot, HSPrognosis group   +10 more
openaire   +6 more sources

IgA vasculitis (Henoch-Schönlein purpura) [PDF]

Dermatology Online Journal, 2015
We report the first case of direct immunoflourescence-proven immunoglobulin A (IgA) vasculitis associated with influenza infection in an adult patient. IgA vasculitis, which was previously known as Henoch-Schönlein purpura, is the most common systemic vasculitis in children but rarely occurs in adults. Disease onset often occurs after upper respiratory
Farhadian, Joshua A, Castilla, Carmen, Shvartsbeyn, Marianna, Meehan, Shane A, Neimann, Andrea, Pomeranz, Miriam Keltz   +5 more
openaire   +5 more sources

New primary renal diagnosis codes for the ERA-EDTA [PDF]

, 2012
The European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry has produced a new set of primary renal diagnosis (PRD) codes that are intended for use by affiliated registries. It is designed specifically for use in renal
Boeschoten, E., Casino, F., Collart, F., Cornet, R., De Meester, J., Gao, Y., Gronhagen-Riska, C., Jacquelinet, C., Jager, K.J., Kramar, R., Reid, C., Schaeffner, E., Simpson, K., Stengel, B., Tomson, C.R.V., Venkat-Raman, G., Zurriaga, O.   +16 more
core   +1 more source

The Aetiology of Elevated Total Serum Immunoglobulin E in Children

Acta Paediatrica, EarlyView.
ABSTRACT Aim The paucity of real‐world data on the aetiology of elevated total serum immunoglobulin E (TS‐IgE) in children afflicts families and health care systems with diagnostic uncertainty. We explored a cohort of children with TS‐IgE levels over 1000 kU/L, focusing on the prevalence of atopic and non‐atopic conditions, the aetiology of extremely ...
Aliisa Ärölä, Kaarina Kukkonen, Svetlana Vakkilainen   +2 more
wiley   +1 more source

Gremlin, a potential urinary biomarker of anca-associated crescentic glomerulonephritis [PDF]

, 2019
Gremlin renal overexpression has been reported in diabetic nephropathy, pauci-immune crescentic glomerulonephritis and chronic allograft nephropathy and has been implicated in the pathophysiology of the progression of renal damage. However, it is unknown
Burgos, María E., Carpio, Daniel, Droguett, Alejandra, Egido, Jesús, Mezzano, Sergio, Ruiz-Ortega, Marta, Saka, Constanza, Valderrama, Graciela   +7 more
core   +2 more sources

Minimal breast milk transfer of rituximab, a monoclonal antibody used in neurological conditions. [PDF]

, 2020
ObjectiveTo determine the transfer of rituximab, an anti-CD20 monoclonal antibody widely used for neurologic conditions, into mature breast milk.MethodsBreast milk samples were collected from 9 women with MS who received rituximab 500 or 1,000 mg ...
Anderson, Annika, Bevan, Carolyn, Bove, Riley, Hale, Thomas W, Krysko, Kristen M, LaHue, Sara C, Marcus, Jacqueline, Riley, Claire S, Rowles, William, Rutatangwa, Alice, Schubert, Ryan D   +10 more
core   +1 more source

Annular Leukocytoclastic Vasculitis: A New Feature of IgA Vasculitis. [PDF]

Eur J Case Rep Intern Med
Background: Annular erythema is a rare manifestation of leukocytoclastic vasculitis. It may be associated with various drugs, infections, malignancies, or systemic diseases. Case description: A 36-year-old woman with no personal medical history presented with annular erythema with target lesions and petechial purpura.
Belfeki N, Ghriss N, Kammoun S, Zayet S, Moini C, Terrier B.   +5 more
europepmc   +4 more sources

Acute Hemorrhagic Edema of Infancy [PDF]

, 2016
Acute Hemorrhagic Edema of Infancy is a small vessel leucocytoclastic vasculitis affecting young infants. It is characterized by large, target-like, macular to purpuric plaques predominantly affecting the face, ear lobes and extremities.
Amaro, C, Garcia, C, Sokolova, A, Torre, ML   +3 more
core   +1 more source