Results 71 to 80 of about 276,806 (364)

The discovery of IgE [PDF]

Journal of Allergy and Clinical Immunology, 2016
In 1919, the search began for the factor, later called reagin, that could mediate an allergy, such as allergic asthma, in sera of allergic subjects. In 1967, the fifth class of immunoglobulins, IgE, was discovered and found to be able to carry reagin activity.
openaire   +2 more sources

Is IgE or eosinophils the key player in allergic asthma pathogenesis? Are we asking the right question?

Respiratory Research, 2018
Bronchial asthma (BA) is a chronic inflammatory disease with a marked heterogeneity in pathophysiology and etiology. The heterogeneity of BA may be related to the inducing mechanism(s) (allergic vs non-allergic), the histopathological background ...
A. Matucci, A. Vultaggio, E. Maggi, I. Kasujee   +3 more
semanticscholar   +1 more source

Ascaris lumbricoids Infection as a Risk Factor for Asthma and Atopy in Rural Bangladeshi Children. [PDF]

, 2014
Controversy persists as to whether helminth infections cause or protect against asthma and atopy. The aim of this study was to investigate the effects of helminth infection on asthma and atopy among Bangladeshi children.
Persson, Lars Å, Noguchi, Emiko,, Itoh, Makoto,, Noguchi, Emiko, Wagatsuma, Yukiko,, Raqib, Rubhana,, Wagatsuma, Yukiko, Ma, Enbo, Moore, Sophie E; id_orcid, Moore, Sophie E,, Moore, Sophie E, Persson, Lars-Åke,, Raqib, Rubhana, Hawlader, Mohammad D H, Hawlader, Mohammad D H,, Arifeen, Shams E,, Arifeen, Shams E, Ma, Enbo,, Itoh, Makoto, Hawlader, Mohammad DH   +19 more
core   +1 more source

IgE-based cancer immunotherapy [PDF]

, 2022
Anti-tumour effect of monoclonal antibodies (mAbs) can be achieved through different mechanisms in which both target engagement with Fab arm and Fc-mediated recruitment of effector immune cells play an important role.
Vuković, Nataša
core   +1 more source

Effect of heating and glycation on the allergenicity of 2S albumins (Ara h 2/6) from peanut [PDF]

, 2011
Although no effect of processing on T-cell reactivity was observed, heat induced denaturation reduced the IgE reactivity and subsequent functionality of Ara h 2/6.
Mills Clare E. N., Vissers, Yvonne M., Ad P H Jansen, Przybylski-Nicaise Laetitia, Wal, J M, Johnson, P.E., Johnson, PE, Savelkoul, H.F.J., Jansen, A.P.H., Przybylski-Nicaise, L, Adel-Patient Karine, Rigby, NM, Jansen Ad P. H., Blanc, Fany, Ballmer-Weber Barbara, Rigby, Neil M., Yvonne M Vissers, Wal, Jean-Michel, Vissers, Y.M., Wichers Harry J., Alan R. Mackie, Clare E N Mills, Skov, Per Stahl, Mills, Clare E. N., Vissers Yvonne M., Barbara Ballmer-Weber, Zuidmeer-Jongejan Laurian, Clare E. N. Mills, Vissers, Y M, Blanc, F., Szepfalusi, Z., Blanc, F, Laetitia Przybylski-Nicaise, Johnson Phil E., Bernhard, H., Harry J. Wichers, Ballmer-Weber, Barbara, Mills, C E N, Wal Jean-Michel, Skov, P S, Rigby, N M, Per Stahl Skov, Yvonne M. Vissers, Skov, PS, Mackie, A R, Jean-Michel Wal, Ballmer-Weber, B, Rigby, N.M., Johnson, Phil E., Wichers, Harry J., Fany Blanc, Adel-Patient, Karine, Ruinemans-Koerts, J., Mills, E.N.C., Karine Adel-Patient, Jansen, A P H, Vissers, YM, Ruinemans-Koerts, Janneke, Zuidmeer-Jongejan, Laurian, Huub F. J. Savelkoul, Phil E Johnson, Wal, Jean Michel, Savelkoul, HFJ, Stahl Skov, P., Przybylski-Nicaise, Laetitia, L., Adel-Patient, K., Ruinemans-Koerts, J, Wal, J-M, Zuidmeer-Jongejan, L., Rigby Neil M., Jansen, APH, Mackie, A.R., Ad P. H. Jansen, Mackie Alan R., Mackie, Alan R., Jansen, Ad P. H., Wichers, HJ, Johnson, P E, Bernard, Hervé, Wichers, H.J., Przybylski-Nicaise, Laetitia, Blanc Fany, Jansen, Ad P H, Neil M Rigby, Neil M. Rigby, Ballmer-Weber, B., Savelkoul, H F J, Harry J Wichers, Skov Per Stahl, Savelkoul Huub F. J., Szépfalusi, Z, Szépfalusi, Zsolt, Przybylski-Nicaise, L., Wichers, H J, Janneke Ruinemans-Koerts, Savelkoul, Huub F. J., Savelkoul, Huub F J, Bernard, H, Mills, CEN, Hervé Bernard, Alan R Mackie, Zsolt Szépfalusi, Phil E. Johnson, Huub F J Savelkoul, Adel-Patient, K, Szépfalusi Zsolt, Wal, J.M., Bernard Hervé, Ruinemans-Koerts Janneke, Mackie, AR, Laurian Zuidmeer-Jongejan, Wal, Jean-Michel, J.-M., Zuidmeer-Jongejan, L, Mills, Clare E N   +113 more
core   +1 more source

IgE-producing TLOs, activated MCs and intramural haematomas are in close proximity in human AAAs.

, 2023
(A) Cross-sections of AAAs were coloured with Perl’s+DAB staining and nucleus were counter-stained with nuclear fast red. TLOs (circled with dashed line) are found at proximity of haematomas (arrowheads). Scale bar: 500 μm.
Marion Morvan (528435), Alexia Loste (17592915), Marie Le Borgne (337225), Sandrine Delbosc (134537), Jean-Marc Alsac (353325), Antonino Nicoletti (268886), Jean-Baptiste Michel (134547), Grégory Gautier (17592927), Liliane Louedec (134540), Raphaël Coscas (17022540), Anh-Thu Gaston (349170), Michel Arock (91968), Yves Castier (342269), Guillaume Even (17592924), Pierre Launay (280563), Emanuele Procopio (2853440), Catherine Deschildre (680144), Lydia Deschamps (776328), Marc Clément (17592918), Kevin Guedj (680142), Jean Sénémaud (17592921), Alexander Eggel (17592930), Giuseppina Caligiuri (349172)   +22 more
core   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

EEG in genetic generalized epilepsies

Эпилепсия и пароксизмальные состояния, 2020
Genetic, or idiopathic, generalized epilepsies (GGEs or IGEs) includes childhood absence epilepsy (CAE), juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and epilepsy with generalized tonic-clonic seizures alone (GTCS-a).Aim.
V. Yu. Nogovitsyn, A. A. Sharkov
doaj   +1 more source

Mimotope mapping as a complementary strategy to define allergen IgE-epitopes: peach Pru p 3 allergen as a model.

, 2008
Lipid transfer proteins (LTPs) are the major allergens of Rosaceae fruits in the Mediterranean area. Pru p 3, the LTP and major allergen of peach, is a suitable model for studying food allergy and amino acid sequences related with its IgE-binding ...
Tordesillas Villuendas, Leticia, Sánchez-Monge Laguna de Rins, Rosa, Palacín Gómez, Aranzazu, Salcedo Duran, Gabriel, Pacios, Luis F., Compes, Esther, Díaz Perales, Araceli, Cuesta-Herranz, Javier   +7 more
core   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source