Results 151 to 160 of about 29,874,260 (303)
IGF-1 colocalizes with muscle satellite cells following acute exercise in humans
Insulin-like growth factor-1 (IGF-1) regulates stem cell proliferation and differentiation in vitro. The aim of this study was to quantify the change in satellite cell (SC) specific IGF-1 colocalization following exercise.
Stuart M Phillips (10488641) +6 more
core
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
Review of articular cartilage repair techniques and their application in the horse
Abstract Articular cartilage lesions represent a significant career‐limiting problem in athletic horses. A healthy articular cartilage surface is vital for optimal joint function, and defects can result in irreversible degenerative changes. Successful treatment of cartilage lesions remains a long‐standing challenge for orthopaedic surgeons, prompting ...
Charlotte K. Barton +2 more
wiley +1 more source
Proteomic signatures of equine dental tooth tissues in ageing and disease
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen +8 more
wiley +1 more source
Genes and proteins involved in insulin-like growth factor (IGF)-1 signaling are thought to be differentially expressed in older versus younger mammalian skeletal muscle following acute exercise. The purpose of this study was to examine how multiple bouts
K Sunderland (9890504) +8 more
core
Composition of allogeneic equine orthobiologics and their repeated intra‐articular administrations
Abstract Background Orthobiologics such as platelet‐rich plasma (PRP) and alpha‐2‐macroglobulin (A2MG) are increasingly used for equine musculoskeletal injuries. However, their composition and safety with repeated allogeneic intra‐articular administration remain poorly investigated.
Yanne Van Reusel +7 more
wiley +1 more source
Translational Development of Physiologic IGF-1 Replacement for the Prevention of Bronchopulmonary Dysplasia. [PDF]
Niklas V, Barton N.
europepmc +1 more source
Under‐Explored Species, Breeds and Cell Types With Potential for Cultivated Meat Production
This graphical abstract illustrates how the strategic selection of overlooked cell lines from novel species and specific agricultural breeds can help overcome current manufacturing bottlenecks in cultivated meat production. The schematic links the concept of an ‘ideal cell line’ to four key bioprocessing and product advantages that can be optimised ...
William Gordon‐Petrovskii +6 more
wiley +1 more source
EGR1 regulates IGF-1-stimulated pancreatic cancer cell invasion by increasing IL-11 expression. [PDF]
Choi Y, Jung E, Han J, Shin SY.
europepmc +1 more source

