Results 141 to 150 of about 30,609,190 (316)
, 2001 Peroxisome proliferator-activated receptor alpha (PPARalpha) plays a central role in glucose and lipid homeostasis. Mice lacking PPARalpha(-/-) have a sexually dimorphic phenotype.
Brismar, K, +7 more
core +1 more source
Proliferative and survival pathways in oesophageal cancer [PDF]
, 2011 Includes abstract.Includes bibliographical references.Oesophageal squamous cell carcinoma (OSCC) is the 8th most common cancer worldwide with high incidence in areas that include China, Iran and South Africa. The current treatment available for OSCC does
Esau, Luke Emmanuel
core +1 more source
Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading
Advanced Science, EarlyView.Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong +5 more
wiley +1 more source
Presence of IGF-1 receptor and insulin receptor (IGF-1R/INSR) hybrid in corneal epithelium.
, 2012 (A) Reciprocal immunoprecipitation (IP) of IGF-1 receptor and insulin receptor in the hTCEpi cell line. Whole cell lysates were subjected to IP with antibodies against either the IGF-1 receptor (IGF-1R) β-subunit (CST#3027) or the insulin receptor (INSR)
Danielle M. Robertson (145361) +2 more
core +1 more source
Animal Models and Experimental Medicine, EarlyView.Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley +1 more source
The “costly son” hypothesis: Sons exacerbate obstetrical dilemmas in humans and other mammals
The Anatomical Record, EarlyView.Abstract Human childbirth has often been considered uniquely difficult among mammals, yet recent evidence suggests that obstructed labor and fetopelvic disproportion are widespread across placental mammals. Here, we propose the “costly son” hypothesis: because male offspring are typically larger at birth, they impose greater obstetric risk on mothers ...
Nicole D. S. Grunstra +1 more
wiley +1 more source
Animal Research and One Health, EarlyView.Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke +9 more
wiley +1 more source
Níveis sérico de IGF-I e IGFBP-3 em pacientes admitidos por complicações da cirrose hepática [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Mestrado Profissional Associado à Residência Médica em Cuidados Intensivos e PaliativosIntrodução: IGF-I e IGFBP-3 fazem parte do sistema IGF e, por terem ...
Ronsoni, Marcelo Fernando
core
Follicle Stimulating Hormone in Cattle Breeding: Fundamentals, Innovations, and Scope
Animal Research and One Health, EarlyView.FSH is crucial in cattle reproduction, with exogenous administration enhancing breeding and embryo production. Recombinant FSH offers advantages over pituitary‐extracted variants, including fewer injections, reduced stress, and safer production. These innovations improve breeding efficiency, optimize reproductive outcomes, and contribute to sustainable
Muhammad Shahzad +7 more
wiley +1 more source