How Much Insulin-Like Growth Factor I (IGF-I) Circulates? Impact of Standardization on IGF-I Assay Accuracy [PDF]
Valerie Quarmby
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New insights into epileptic spasm generation and treatment from the TTX animal model
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann+2 more
wiley +1 more source
The Impact of Westernization on the Insulin/IGF-I Signaling Pathway and the Metabolic Syndrome: It Is Time for Change. [PDF]
Janssen JAMJL.
europepmc +1 more source
Proteolysis of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in 150-kilodalton IGFBP complexes by a cation-dependent protease activity in adult rat serum promotes the release of bound IGF- I [PDF]
C. Y. Lee
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ABSTRACT Background and objective Anorexia nervosa (AN) is a mental disorder most prevalent among adolescent females, with rising cases in younger and more culturally diverse populations. Unhealthy activity patterns are common and have been linked to increased relapse rates; however, data on objectively measured physical activity levels (PALs) in this ...
Álex V. Pagador+4 more
wiley +1 more source
Activation of integrin and ceramide signalling pathways can inhibit the mitogenic effect of insulin-like growth factor I (IGF-I) in human breast cancer cell lines [PDF]
Claire M. Perks+3 more
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ABSTRACT Background Anorexia nervosa (AN) is a severe psychiatric disorder with high mortality, requiring innovative treatment strategies. Olanzapine (OLZ), an atypical antipsychotic, has demonstrated efficacy in promoting weight gain and reducing psychopathological symptoms in adults with AN.
Helene Krauss+10 more
wiley +1 more source
Up IGF-I via high-toughness adaptive hydrogels for remodeling growth plate of children. [PDF]
Zhang Z+6 more
europepmc +1 more source