Results 351 to 360 of about 14,093,235 (401)
Some of the next articles are maybe not open access.
Acta Endocrinologica, 1987
Abstract. Binding of 125I-insulin-like growth factor-I and 125I-ovine somatomedin-C/IGF-I to monolayer cultures of muscle-derived ovine fibroblasts is described. Preliminary competitive binding experiments indicate that ovine fibroblasts possess independent cell surface receptors for IGF-I.
M V, Dodson, B A, Mathison, K L, Hossner
openaire +2 more sources
Abstract. Binding of 125I-insulin-like growth factor-I and 125I-ovine somatomedin-C/IGF-I to monolayer cultures of muscle-derived ovine fibroblasts is described. Preliminary competitive binding experiments indicate that ovine fibroblasts possess independent cell surface receptors for IGF-I.
M V, Dodson, B A, Mathison, K L, Hossner
openaire +2 more sources
2018
Growth hormone (GH) and insulin-like growth factor-I (IGF-I) are relevant regulators of bone homeostasis throughout human life, acting on both the trabecular and cortical bone [1]. The anabolic effects of these hormones are important to reach an adequate bone mass during puberty and early adulthood—a critical determinant for the future risk of ...
Frara, Stefano +5 more
openaire +2 more sources
Growth hormone (GH) and insulin-like growth factor-I (IGF-I) are relevant regulators of bone homeostasis throughout human life, acting on both the trabecular and cortical bone [1]. The anabolic effects of these hormones are important to reach an adequate bone mass during puberty and early adulthood—a critical determinant for the future risk of ...
Frara, Stefano +5 more
openaire +2 more sources
Molecular Reproduction and Development, 1993
AbstractConstitutive overexpression of the insulin‐like growth factor‐I (IGF‐I) receptor makes 3T3 cells capable of growing in serum‐free medium supplemented solely with IGF‐I to the total exclusion of the platelet‐derived growth factor (PDGF) and epidermal growth factor (EGF) receptors, the other two receptors that are required for the growth of 3T3 ...
openaire +2 more sources
AbstractConstitutive overexpression of the insulin‐like growth factor‐I (IGF‐I) receptor makes 3T3 cells capable of growing in serum‐free medium supplemented solely with IGF‐I to the total exclusion of the platelet‐derived growth factor (PDGF) and epidermal growth factor (EGF) receptors, the other two receptors that are required for the growth of 3T3 ...
openaire +2 more sources
Utility of Free IGF-I Measurements
Pituitary, 2007For nearly 30 years, the endogenous bioactivity of insulin-like growth factor I (IGF-I) has been estimated by its circulating concentrations of immunoreactive IGF-I, obtained after either removal or inactivation of the IGF-binding proteins (IGFBPs), and today serum/plasma total IGF-I serves as a useful parameter in the diagnosis and clinical control of
openaire +3 more sources
1991
As the significance of putative intraovarian regulators becomes increasingly recognized, much of the attention centers on insulin-like growth factors (IGFs). Indeed, a large body of evidence now suggests the existence of an intraovarian IGF system complete with ligands, receptors, and binding proteins.
Eli Y. Adashi +6 more
openaire +1 more source
As the significance of putative intraovarian regulators becomes increasingly recognized, much of the attention centers on insulin-like growth factors (IGFs). Indeed, a large body of evidence now suggests the existence of an intraovarian IGF system complete with ligands, receptors, and binding proteins.
Eli Y. Adashi +6 more
openaire +1 more source
Clinical proteomics: Insights from IGF-I
Clinica Chimica Acta, 2018Clinical proteomics aims to deliver cost-effective multiplexing of potentially hundreds of diagnostic proteins, including distinct protein isoforms. The analytical strategy known as targeted proteomics is particularly promising because it is compatible with robust mass spectrometry (MS)-platforms already implemented in many clinical laboratories for ...
Albrethsen, Jakob +4 more
openaire +3 more sources
IGF I Receptor Phosphorylation
1989Physiologically, cells are simultaneously exposed to a plethora of hormones. The way in which a cell responds to stimulation by a specific hormone depends not only upon the concentration of that hormone, but upon the presence of other hormones as well.
Cary Moxham +2 more
openaire +1 more source
Nutrition Clinique et Métabolisme, 1996
Resume De nombreux effets anaboliques de l'hormone de croissance (GH) sont induits par l' Insulin-like Growth Factor-1 (IGF-I), polypeptide mitogenique presentant des similitudes structurales avec l'insuline. Les concentrations plasmatiques de l'IGF-I varient selon l'etat nutritionnel, la situation metabolique et les pathologies presentes.
openaire +1 more source
Resume De nombreux effets anaboliques de l'hormone de croissance (GH) sont induits par l' Insulin-like Growth Factor-1 (IGF-I), polypeptide mitogenique presentant des similitudes structurales avec l'insuline. Les concentrations plasmatiques de l'IGF-I varient selon l'etat nutritionnel, la situation metabolique et les pathologies presentes.
openaire +1 more source
Intraovarian regulation: the IGF-I example
Reproduction, Fertility and Development, 1992A large body of information now supports the existence of an intraovarian system of insulin-like growth factors (IGFs) replete with ligands, receptors, and binding proteins. The intraovarian IGF system is most likely concerned with the amplification of gonadotrophin hormonal action, other potential regulatory roles remaining speculative at this time ...
openaire +2 more sources