Results 111 to 120 of about 29,583 (184)

Unidirectional Crosstalk Between NTRK1 and IGF2 Drives ER Stress in Chronic Pain

Biomedicines
Background: Chronic postsurgical pain (CPSP) poses a major clinical challenge due to unresolved links between neurotrophic pathways and endoplasmic reticulum (ER) stress.
Caixia Zhang, Kaiwen Zhang, Wencui Zhang, Bo Jiao, Xueqin Cao, Shangchen Yu, Mi Zhang, Xianwei Zhang   +7 more
doaj   +1 more source

Cloning of Breakpoints in and Downstream the Igf2 Gene That Are Associated with Overexpression of Igf2 Transcripts in Colorectal Tumours

, 1999
peer reviewedThe human IGF2 gene belongs to a group of imprinted genes clustered on the short arm of chromosome 11, band p15.5. It contains 9 exons and spans over 30 kb.
Delneuville, Delphine, Hodzic, D., Scarcez, T., Grooteclaes, M., Winkler, Rose, Frey, B.   +5 more
core   +1 more source

Genotype-Epigenotype Interaction at the IGF2 DMR

, 2015
Paternally expressed Insulin-like Growth Factor II (IGF2) encodes a gene whose protein product functions as a potent growth mitogen. Overexpression of IGF2 has been implicated in a wide number of disorders and diseases.
Susan Murphy, Erin Erginer, Zhiqing Huang, Zachary Visco, Cathrine Hoyo   +4 more
core   +1 more source

IGF2/H19 Expression in Placenta.

, 2016
(A)The expression of IGF2 in placenta was significantly higher in GDM group than that in NGT group. (B) The expression of IGF2 in placenta was significant higher in NGT-M group than NGT-NBW group. (C)The expression of H19 in placenta from GDM group had a
Huixia Yang (169169), Rina Su (520454), Hui Feng (174331), Chen Wang (88408), Li Lin (111038), Xinyue Liu (170148), Yumei Wei (2164540)   +6 more
core   +1 more source

BPA exposure altered DNA methylation at the Igf2 DMR1 and H19/Igf2 ICR in the embryos.

, 2013
A. Pyrosequencing assays tested methylation of 4 and 6 CpGs (highlighted in bold) in 457 bp and 221 bp genomic regions at the Igf2 DMR1 and H19/Igf2 ICR, respectively.
Martha Susiarjo (23984), Isaac Sasson (399544), Clementina Mesaros (399545), Marisa S. Bartolomei (328035)   +3 more
core   +1 more source

Paradoxical regulation of IGF2 in promoting lipid metabolism in adipose tissues

Communications Biology
Metabolic diseases such as diabetes, obesity, and dyslipidemia pose major public health challenges globally. While the insulin-like growth factor 2 (IGF2) gene is known to be involved in various physiological processes, its precise role in lipid ...
Caiping Zhou, Weiwei Gui, Weifen Zhu, Hanxin Zhao, Dingting Wu, Fang Wu, Gangliang Wang, Xihua Lin   +7 more
doaj   +1 more source

Optimalizace interakce IGF2 s jeho receptorem [PDF]

Protein-protein interactions are a key aspect of biochemical processes, as they play a crucial role in the development of various diseases. However, experimental studies of these interactions are often time-consuming and technically challenging. For this
Mrzílková, Karolína
core  

Effects of Partial Myostatin Loss of Function on Carcass Yield and Meat Quality in Pigs Differing in IGF2 Genotype. [PDF]

Animals (Basel)
Burris ES, Honegger LT, Boler DD, Beever JE, Dilger AC.   +4 more
europepmc   +1 more source

Persistent postnatal IGF2 expression alters adult skeletal architecture in <i>Igf2</i> ^<i>G/A</i> mice. [PDF]

Bone Rep
Younis S, Shimonty A, Perez-Menendez S, You X, Sridevan SM, Ben-Tahar S, Andrews H, Shefelbine S, Andersson L, Charles JF.   +9 more
europepmc   +1 more source

Insulin-like growth factor receptor signaling in physiology and disease. [PDF]

Signal Transduct Target Ther
Dilawar M, Malik A, Liao J, Shen P, Huang Z, Zhang P, Wang J, Zhang N, Nisar MF, Chen G.   +9 more
europepmc   +1 more source