Results 101 to 110 of about 29,583 (184)

Pig IGF2 GWAS

open access: yes, 2019
Analysis of porcine IGF2 gene expression in adipose tissue and its effect on fatty acid ...
Lourdes Criado-Mesas (6713812)   +1 more
core   +1 more source

278. IGF2 polymorphisms predict pregnancy outcome

open access: yes, 2008
IGF-II is an important determinant of placental trophoblast invasion and subsequent placental function. IGF-II can act in autocrine/paracrine and endocrine fashions to promote placental invasion and differentiation and within both the fetus and ...
S. D. Thompson   +4 more
core   +1 more source

IGF2: Epigenetic regulation and role in development and disease [PDF]

open access: yes, 2018
Insulin-like growth factor II (IGF2) is perhaps the most intricately regulated of all growth factors characterized to date. Its gene is imprinted—only one allele is active, depending on parental origin—and this pattern of expression is maintained ...
Chao, Wendy, D'Amore, Patricia
core   +1 more source

Mechanisms accounting for variant IGF2 proteins.

open access: yes, 2019
A. Amino acid sequences of a mammalian IGF2 variants with 70 or 71 amino acids are depicted in single letter code. The additional residues are underlined for human IGF2. Dots depict identities, and differences among species are indicated.
Kabita Baral (6894350)   +1 more
core   +1 more source

Alignments of IGF2 E peptides.

open access: yes, 2019
Amino acid sequences of COOH-terminal IGF2 E peptides from 19 mammals are depicted in single letter code. Dots indicate identities, dashes depict no residues, and differences among species are shown. The IGF2 E domain comprises different lengths, ranging
Kabita Baral (6894350)   +1 more
core   +1 more source

Analysis of porcine IGF2 gene expression in adipose tissue and its effect on fatty acid composition.

open access: yesPLoS ONE, 2019
IGF2:g.3072G>A polymorphism has been described as the causal mutation of a maternally imprinted QTL for muscle growth and fat deposition in pigs. The objective of the current work was to study the association between the IGF2:g.3072G>A polymorphism and ...
Lourdes Criado-Mesas   +6 more
doaj   +1 more source

Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting.

open access: yes, 2006
The potent growth-promoting activity of insulin-like growth factor-II (IGF-II) is highly regulated during development but frequently up-regulated in tumors.
Foulstone, EJ   +7 more
core   +1 more source

Activation of the insulin receptor by insulin-like growth factor 2

open access: yesNature Communications
Insulin receptor (IR) controls growth and metabolism. Insulin-like growth factor 2 (IGF2) has different binding properties on two IR isoforms, mimicking insulin’s function.
Weidong An   +8 more
doaj   +1 more source

STAT3-dependent upregulation of IGF2 in TSC2-null cells.

open access: yes, 2018
(A) Re-expression of TSC2 (TSC2++) in TSC2-null LAM 102 (TSC2—) cells decreased STAT3 expression and activation. (B) siRNA-induced knockdown of STAT3 decreased STAT3 levels in TSC2— cells.
Maya Shumyatcher (5215781)   +9 more
core   +1 more source

IGF2 knockdown restores Taxol sensitivity.

open access: yes, 2014
(A) Taxol sensitivity after IGF2 knockdown by siRNA. HEY-T30 and A2780-T15 cells were transfected with control nontargeting siRNA (siCTRL) or siRNAs targeting IGF2 (siIGF2-1, siIGF2-2, siIGF2-3), and treated with DMSO or Taxol at the approximate IC50 ...
Gloria S. Huang (578689)   +5 more
core   +1 more source

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