Results 81 to 90 of about 29,583 (184)
Glia, Volume 74, Issue 11, November 2026.ATP1B2 and GLAST identify two astrocyte subpopulations in the hippocampus with distinct molecular signatures. Transcriptomic shifts during aging differ between both subpopulations. Aged ATP1B2+ astrocytes rewire their metabolism while double‐positive aged astrocytes display a reduced synaptogenic capability.
Lucía Casares‐Crespo +6 more
wiley +1 more source
IGF signaling pathway activation in IGF2-high and IGF2-low ACC.
, 2014 The activation of Erk (A), Akt (B), and IGF1R/INSR receptors (C) was analyzed by western blotting with antibodies directed against the phosphorylated form of these proteins, in IGF2-high (n = 10) and IGF2-low (n = 10) ACC.
Virginie Steunou (608453) +17 more
core +1 more source
Cell Transplantation, 2012 Insulin-like growth factor II (IGF2) is a growth-promoting peptide that increases β-cell proliferation and survival. The aim of the study was to determine the effect of IGF2 overexpression on β-cell mass in transplanted islets.
Elisabet Estil·les +3 more
doaj +1 more source
, 2009 DNA methylation patterns at the IGF2-H19 locus were investigated in sperm DNA from Swiss Landrace (SL) and Swiss Large White (LW) boars. The putative IGF2 differentially methylated regions (DMR) 0, 1 and 2, a quantitative trait nucleotide (QTN) region in
Braunschweig, M., Giannini, P.
core +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, Volume 20, Issue 10, Page 2510-2532, October 2026.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Advanced Science, Volume 13, Issue 55, 5 October 2026.This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu +10 more
wiley +1 more source
The mouse Igf2—H19 locus and the human IGF2—H19 locus and genes.
, 2019 A. Maps of the mouse Igf2 –H19 locus on chromosome 7 and the human IGF2 –H19 locus on chromosome 11p15.5 with chromosomal coordinates for key features listed.
Kabita Baral (6894350) +1 more
core +1 more source
Expression and protein localisation of IGF2 in the marsupial placenta [PDF]
, 2008 BACKGROUND: In eutherian mammals, genomic imprinting is critical for normal placentation and embryo survival. Insulin-like growth factor 2 (IGF2) is imprinted in the placenta of both eutherians and marsupials, but its function, or that of any imprinted ...
Shaw, G +7 more
core +1 more source
Proteomic Signatures of Noise‐Induced Hearing Loss in the Mouse Cochlea
Cell Biology International, Volume 50, Issue 10, October 2026.ABSTRACT Hearing loss affects over 1.5 billion people worldwide and has substantial social, educational, and economic consequences. Although genetic studies have identified numerous hearing‐loss‐associated genes, the molecular changes accompanying noise‐induced hearing loss (NIHL) remain incompletely understood.
Ana Carla Batissoco +6 more
wiley +1 more source
Исследования и практика в медицинеThe diagnosis of adrenocortical tumors has undergone substantial changes in recent years owing to the introduction of reproducible morphological scoring systems combined with validated immunohistochemical and molecular markers.
D. V. Bulanov +4 more
doaj +1 more source