Results 71 to 80 of about 29,583 (184)

Mouse Igf2 and human IGF2 mRNAs and proteins.

open access: yes, 2019
A, B. Depiction of the 4 major species of mouse Igf2 transcripts (A) and the 6 major types of human IGF2 mRNAs (B). The responsible promoters (p for mouse, P for human) are listed, as are the exons found in each transcript.
Kabita Baral (6894350)   +1 more
core   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

IGF2/Igf2 and H19 gene expression in mammals.

open access: yes, 2019
Data on IGF2/Igf2, H19, and control gene MRPS17/Mrps17 transcript expression in liver was obtained by screening RNA-sequencing libraries found in NCBI SRA (the libraries searched are listed in S1 Table, and the probes used in S2 Table).
Kabita Baral (6894350)   +1 more
core   +1 more source

Medaka insulin-like growth factor-2 supports self-renewal of the embryonic stem cell line and blastomeres in vitro

open access: yesScientific Reports, 2017
Insulin-like growth factors (IGFs) regulate diverse processes including energy metabolism, cell proliferation and embryonic development. They activate the IGF signaling pathway via binding to cell surface receptors.
Yongming Yuan, Yunhan Hong
doaj   +1 more source

Placental mitochondrial metabolic adaptation maintains cellular energy balance in pregnancy complicated by gestational hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong   +18 more
wiley   +1 more source

Overexpression of IGF2 and IGF2 receptor in malignant solitary fibrous tumor with hypoglycemia: a case report

open access: yes, 2018
Background Solitary fibrous tumor (SFT) is a prototypical mesenchymal neoplasm that induces non-islet cell tumor hypoglycemia (NICTH) due to overproduction of insulin-like growth factor 2 (IGF2). We here report the case of a malignant SFT associated with
Takeshi Kuroda   +7 more
core   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda   +5 more
wiley   +1 more source

Alignments of mature IGF2.

open access: yes, 2019
Amino acid sequences of IGF2 (67 or 68 amino acids) from different mammals are illustrated in single letter code. Dots depict identities, and differences among species are indicated. A dash depicts no residue.
Kabita Baral (6894350)   +1 more
core   +1 more source

Insulin‐like growth factor 2: a poor prognostic biomarker linked to racial disparity in women with uterine carcinosarcoma

open access: yesCancer Medicine, 2018
The objective of this study was to investigate the relationship of insulin‐like growth factor 2 (IGF2) expression and survival in women with uterine carcinosarcoma (UCS).
Anne R. Van Arsdale   +8 more
doaj   +1 more source

Relationship of porcine IGF2 imprinting status to DNA methylation at the H19 DMD and the IGF2 DMRs 1 and 2

open access: yes, 2011
BACKGROUND: Porcine IGF2 and the H19 genes are imprinted. The IGF2 is paternally expressed, while the H19 gene is maternally expressed. Extensive studies in mice established a boundary model indicating that the H19 differentially methylated domain (DMD ...
Stahlberger, Nasikhat   +2 more
core   +1 more source

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