Follicle-Stimulating Hormone Regulates igfbp Gene Expression Directly or via Downstream Effectors to Modulate Igf3 Effects on Zebrafish Spermatogenesis [PDF]
Frontiers in Endocrinology, 2017 Previous work showed that pharmacological inactivation of Igf-binding proteins (Igfbps), modulators of Igf activity, resulted in an excessive differentiation of type A undifferentiated (Aund) spermatogonia in zebrafish testis in tissue culture when Fsh ...
Diego Safian +2 more
exaly +16 more sources
Analysis of circRNA and miRNA expression profiles in IGF3-induced ovarian maturation in spotted scat (Scatophagus argus) [PDF]
Frontiers in Endocrinology, 2022 Insulin-like growth factor 3 (IGF3) induces ovarian maturation in teleosts; however, research on its molecular regulatory mechanism remains deficient. Circular RNAs (circRNAs) and microRNAs (miRNAs) are involved in various biological processes, including
Zhiyuan Li +13 more
doaj +5 more sources
Characterization and expression analysis of gonad specific igf3 in the medaka ovary
Aquaculture and Fisheries, 2022 The gonad specific expression of insulin-like growth factor 3 (igf3) has suggested an important role of igf3 in fish reproduction. In this study, medaka igf3 was isolated and its expression patterns were compared with igf1, and germ cell gene vasa in ...
Lang Gui, Mingyou Li
exaly +5 more sources
Regulation of spermatogenesis and reproductive capacity by Igf3 in tilapia [PDF]
Cellular and Molecular Life Sciences, 2020 A novel insulin-like growth factor (igf3), which is exclusively expressed in the gonads, has been widely identified in fish species. Recent studies have indicated that Igf3 regulates spermatogonia proliferation and differentiation in zebrafish; however, detailed information on the role of this Igf needs further in vivo investigation.
Minghui Li, Xingyong Liu, Shengfei Dai
exaly +5 more sources
A Novel igf3 Gene in Common Carp (Cyprinus carpio): Evidence for Its Role in Regulating Gonadal Development [PDF]
PLoS ONE, 2016 Since the insulin-like growth factor 3 (igf3) gene was recently discovered in fish ovary, its function in the gonads has received much attention. In this study, we isolated two igf3 subtypes from common carp (Cyprinus carpio), which comprised full-length
Jianjun Fu, Zai-jie Dong
exaly +6 more sources
Sexual dimorphic effects of igf1 deficiency on metabolism in zebrafish [PDF]
Frontiers in Endocrinology, 2022 Insulin-like growth factor 1 (IGF1) is an essential effector of the growth hormone (GH)/IGF1 axis for somatic growth regulation in mammals. However, its functions have not been thoroughly investigated in zebrafish in vivo.
Ningmei Zeng +14 more
doaj +6 more sources
Long noncoding RNA and mRNA expression profiles following igf3 knockdown in common carp, Cyprinus carpio [PDF]
Scientific Data, 2019 AbstractAs a novel IGF system member, igf3 plays an important role in gonadal development of teleost fish. Although studies have reported the unusual expression of igf3 in fish gonad, whether the igf3 affects the expression of long noncoding RNAs (lncRNAs) in gonad remains unknown.
Zai-jie Dong
exaly +6 more sources
The Expression Pattern of Insulin-Like Growth Factor Subtype 3 (igf3) in the Orange-Spotted Grouper Epinephelus coioides and Its Function on Ovary Maturation. [PDF]
Int J Mol Sci, 2023 A new insulin-like growth factor (Igf) subtype 3 (igf3) has recently been found in the bony fish orange-spotted grouper (Epinephelus coioides). However, the role of igf3 in the maturation of the ovary and sex differentiation in E. coioides is currently unknown.
Jiao F +7 more
europepmc +4 more sources
Aquaculture Reports, 2022 Insulin-like growth factor 3 (IGF3) has been found to induce ovarian maturation in teleost, but its molecular regulatory mechanism remains unknown.
Yaorong Wang +8 more
exaly +4 more sources
Entry into puberty is reflected in changes in hormone production but not in testicular receptor expression in Atlantic salmon (Salmo salar) [PDF]
Reproductive Biology and Endocrinology, 2019 Background Puberty in male Atlantic salmon in aquaculture can start as early as after the first winter in seawater, stunts growth and entails welfare problems due to the maturation-associated loss of osmoregulation capacity in seawater.
Rüdiger W. Schulz +6 more
doaj +6 more sources