Results 91 to 100 of about 45,932 (257)

TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum

Insect Science, EarlyView.
RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li, Jie Chen, Zi‐Ye Wang, Fei‐Feng Wang, Lu‐Lu Dong, Jun Pan, Min‐Er Li, Lin Yu, Wen Sang   +8 more
wiley   +1 more source

Cloning of salmon IGFBP-1 [PDF]

, 2005
Western ligand blotting of salmon serum typically reveals three insulin-like growth factor binding proteins (IGFBPs) at 22, 28 and 41 kDa. Physiological regulation of the 22-kDa IGFBP is similar to that of mammalian IGFBP-1; it is increased under ...
Shimizu, M., Dickhoff, W W, Dickey, J T, Fukada, H.   +3 more
core   +1 more source

Genome‐wide association and interaction analysis for proliferative retinopathy in adults with type 2 diabetes born during famine: The DOLCE study in Ukraine

Acta Ophthalmologica, EarlyView.
Abstract Purpose Proliferative diabetic retinopathy (PDR) is one of the leading causes of blindness in working‐age adults. We have previously shown that the risk of PDR is significantly elevated in individuals with intrauterine exposure to famine. However, the genetic mechanisms mediating this association remain unknown.
Olena Fedotkina, Most Champa Begum, Xuan Tung Trinh, Turkuler Özgumus, Mikael Åkerlund, Peter Nilsson, Leticia Maria Spindola, Valeriya Lyssenko   +7 more
wiley   +1 more source

Comparative expression profiling of insulin-like growth factor binding protein-5 in milk of Bos indicus and Bubalus bubalis during lactation

Animal, 2015
Insulin-like growth factor binding protein-5 (IGFBP-5) is a key molecule in mammary gland development, which facilitates the removal of mammary epithelial cells (MECs) by apoptosis that takes place during remodeling of the mammary gland during involution.
S.K. Mohapatra, S. Singh, S. Kumar, A.K. Dang, T.K. Datta, S.K. Das, T.K. Mohanty, J.K. Kaushik, A.K. Mohanty   +8 more
doaj   +1 more source

High‐resolution spatial transcriptomic atlas of mouse soleus muscle: Unveiling single cell and subcellular heterogeneity in health and denervation

The FEBS Journal, EarlyView.
Seq‐Scope maps skeletal muscle transcriptomes at high spatial resolution while preserving histological context, revealing distinct responses of myofibers, neuromuscular junctions, and stromal cells to denervation. This spatial view uncovers fiber type‐specific and localized remodeling across intact muscle tissue.
Jer‐En Hsu, Lloyd Ruiz, Yongha Hwang, Steve D. Guzman, Chun‐Seok Cho, Weiqiu Cheng, Yichen Si, Peter Macpherson, Angelo Anacleto, Qingyang Zhao, Xiaoya Zhao, Mitchell Schrank, Goo Jun, Hyun Min Kang, Myungjin Kim, Susan V. Brooks, Jun Hee Lee   +16 more
wiley   +1 more source

IGFBP-3 is a Metastasis Suppression Gene in Prostate Cancer

Cancer Research, 2011
The insulin-like growth factor binding protein IGFBP-3 is a pro-apoptotic and anti-angiogenic protein in prostate cancer (CaP). Epidemiological studies suggest that low IGFBP-3 is associated with greater risk of aggressive, metastatic prostate cancers ...
H. Mehta, Qing-Lei Gao, C. Galet, Vladislava Paharkova, J. Wan, J. Said, Joanne Sohn, G. Lawson, P. Cohen, L. Cobb, Kuk-Wha Lee   +10 more
semanticscholar   +1 more source

Ethylenediaminetetraacetic Acid and Other Dentine Bioactive Molecule‐Releasing Agents for Regenerative Endodontic Procedures: A Systematic Review

International Endodontic Journal, EarlyView.
ABSTRACT Background The bioactive molecules released from dentine are key to stem‐cell recruitment, proliferation and differentiation in regenerative endodontics. However, there is limited and conflicting information regarding current and potential agents for releasing dentine bioactive molecules for regenerative endodontic procedures.
Arwa Al‐Maswary, Xiaoxuan Deng, Haizal M. Hussaini, Lara T. Friedlander, Paul R. Cooper   +4 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Insulin-like Growth Factor-binding Protein-3 (IGFBP-3) Blocks the Effects of Asthma by Negatively Regulating NF-κB Signaling through IGFBP-3R-mediated Activation of Caspases*♦

Journal of Biological Chemistry, 2011
Insulin-like growth factor-binding protein-3 (IGFBP-3) is a multifunctional protein known for modulating mitogenic and metabolic actions of IGFs as well as exerting a variety of biological actions not involving IGFs.
Yong-Chul Lee, Sherryline Jogie‐Brahim, Dae-Yeol Lee, Jin-Feng Han, Aki Harada, L. Murphy, Y. Oh   +6 more
semanticscholar   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source