Results 81 to 90 of about 45,932 (257)

Targeting Renal IGFBP7 With Tetrahedral Framework Nucleic Acid‐Delivered siRNA Alleviates Acute Kidney Injury

open access: yesiNew Medicine, EarlyView.
A tFNA‐based siRNA delivery system targeting IGFBP7 effectively silences IGFBP7 expression and attenuates renal dysfunction, tubular injury, and cell death in both septic (CLP) and ischemic (I/R) murine models of acute kidney injury. ABSTRACT Objective Acute kidney injury (AKI) is a common and serious clinical condition, yet effective targeted ...
Shao‐qi Wu   +11 more
wiley   +1 more source

Prohibitin-2 Binding Modulates Insulin-like Growth Factor-binding Protein-6 (IGFBP-6)-induced Rhabdomyosarcoma Cell Migration*

open access: yesJournal of Biological Chemistry, 2013
Background: As well as inhibiting insulin-like growth factor (IGF) actions, IGF-binding protein (IGFBP)-6 also promotes rhabdomyosarcoma cell migration.
P. Fu, Zhi-Yong Yang, L. Bach
semanticscholar   +1 more source

Salmon IGFBP-1 RIA [PDF]

open access: yes, 2006
Fish plasma/serum contains multiple insulin-like growth factor binding proteins (IGFBPs), although their identity and physiological regulation are poorly understood.
Dickhoff, Walton W.   +2 more
core   +1 more source

Insulin‐Like Growth Factor Axis and Survival in Metastatic Hormone‐Sensitive Prostate Cancer: Post‐Hoc Analysis From the ENZAMET Phase 3 Trial

open access: yesThe Prostate, EarlyView.
ABSTRACT Background A higher ratio of IGF‐1:IGF binding protein 1 (IGFBP1) was associated with improved prognosis in the CHAARTED trial of docetaxel in participants with metastatic hormone‐sensitive prostate cancer (mHSPC). The ENZAMET trial demonstrated the survival benefit of adding enzalutamide to androgen deprivation therapy (ADT) in mHSPC, and ...
Michael A. Cilento   +15 more
wiley   +1 more source

Expression of insulin-like growth factor binding protein-3 in HELLP syndrome

open access: yesBMC Pregnancy and Childbirth, 2023
Objective To investigate the expression of insulin-like growth factor binding protein-3(IGFBP-3) in HELLP syndrome and its possible role in the pathogenesis of this disease. Methods 1) 87 subjects were enrolled, including 29 patients with HELLP syndrome,
Li Wei, Zhou Liping, Kang Suya
doaj   +1 more source

Effects of Green Tea Supplementation on Chemoprevention at Different Stages of Carcinogenesis: A Systematic Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Green tea catechins have chemopreventive potential; however, the clinical evidence remains inconsistent. This review evaluated the effects of supplementation with green tea derivatives on chemoprevention at different stages of carcinogenesis. PubMed, Embase, Web of Science, Scopus, the Cochrane Library, CINAHL, and Google Scholar were searched
Thaís Moreira Machado   +6 more
wiley   +1 more source

Ligand-binding activity and immunoreactivity of insulin-like growth factor binding proteins in patients with colorectal carcinoma and postoperative sepsis [PDF]

open access: yesJournal of Medical Biochemistry, 2013
Background: Postoperative sepsis alters the growth hormone (GH)/insulin-like growth factor (IGF) axis leading to reduction in IGF-I and IGF-binding protein (IGFBP) 3 and elevation of GH-independent IGFBPs.
Nedić Olgica   +3 more
doaj  

Characterization of Insulin-Like Growth Factor Binding Protein-5 (IGFBP-5) Gene and Its Potential Roles in Ontogenesis in the Pacific Abalone, Haliotis discus hannai

open access: yesBiology, 2020
Insulin-like growth factor binding protein family is known to be involved in regulating biological actions of insulin-like growth factors (IGFs). In the present study, a full-length cDNA encoding the IGFBP-5 gene was cloned and characterized from the ...
Md. Rajib Sharker   +3 more
doaj   +1 more source

Insulin-like growth factor binding proteins increase intracellular calcium levels in two different cell lines. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Insulin-like growth factor binding proteins (IGFBPs) are six related secreted proteins that share IGF-dependent and -independent functions.
Danielle Seurin   +4 more
doaj   +1 more source

RIA for salmon IGFBP [PDF]

open access: yes, 2003
Salmon plasma contains at least three insulin-like growth factor binding proteins (IGFBPs) with molecular masses of 41, 28 and 22 kDa. The 41-kDa IGFBP is similar to mammalian IGFBP-3 in size, type of glycosylation and physiological responses.
Shimizu, M., Dickhoff, WW, Hara, A.
core   +1 more source

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