Semi-Quantitative Analysis and Serological Evidence of Hepatitis A Virus IgG Antibody among children in Rumuewhor, Emuoha, Rivers State, Nigeria [PDF]
Hepatitis A virus (HAV) infection has been greatly reduced in most developed countries through the use of vaccine and improved hygienic conditions. However, the magnitude of the problem is underestimated and there are no well-established Hepatitis A virus prevention and control strategies in Nigeria.
arxiv
Antibody-screening methods to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) need to be validated. We evaluated SARS-CoV-2 IgG and IgA ELISAs in conjunction with the EUROLabworkstation (Euroimmun, Lübeck, Germany).
A. Jääskeläinen+7 more
semanticscholar +1 more source
Preparation of IgG Subclass Allotypes from Polyclonal IgG [PDF]
Two allotypes have been identified for each of the IgG subclasses IgG1, IgG2 and IgG3. These allotypes are referred to as G1m(a) and G1m(f), G2m(n) and G2m(‐n), and G3m(g) and G3m(b). Using a pool of normal human serum and a combination of preparative electrophoresis, DEAE ion‐exchange and protein A–Sepharose chromatography, it was possible to separate
openaire +3 more sources
Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis [PDF]
Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA-adducts are part of the natural antibody pool, while elevated levels of IgG anti-MDA are associated with inflammatory conditions.
arxiv +1 more source
Brainstem and cerebellar involvement in MOG-IgG-associated disorder versus aquaporin-4-IgG and MS
Objective To determine the frequency and characteristics of brainstem or cerebellar involvement in myelin-oligodendrocyte-glycoprotein-antibody-associated-disorder (MOGAD) versus aquaporin-4-IgG-seropositive-neuromyelitis optica spectrum disorder (AQP4 ...
Samantha A. Banks+16 more
semanticscholar +1 more source
Heating of X-Ray Hot Gas in Groups by Blast Waves [PDF]
In order to find the conditions which determine whether X-Ray hot gas in galaxy groups (intragroup gas; IGG) is heated externally or internally, we investigate the evolution of blast waves in galaxy groups growing on a hierarchical clustering scenario. We find that the blast waves driven by quasars are confined in groups and heat the IGG internally at ...
arxiv +1 more source
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee+16 more
wiley +1 more source
Investigation of COVID-19 Serology in a Tertiary Care Center
Purpose: This study aimed to screen the patients admitted to our hospital for SARS-CoV-2 specific antibodies after a PCR test and understand the local serological profile.
Pelin ONARER+2 more
doaj +1 more source
Sensitive label-free IgG detection using MEMS QCM biosensor with 125-MHz wireless quartz resonator [PDF]
We present a wireless QCM biosensor fabricated using MEMS technology. The MEMS QCM biosensor contains a 125-MHz AT-cut quartz resonator embedded in the microchannel. Because of the compact design, the MEMS QCM biosensor is suitable for mass production and device miniaturization.
arxiv
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls+9 more
wiley +1 more source