Results 191 to 200 of about 457,033 (338)
Prothrombotic Activation of Platelet Pannexin‐1 Channels in Antiphospholipid Syndrome
Arthritis &Rheumatology, EarlyView.Objective ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. The objective of this study was to evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired ...
Bruna de Moraes Mazetto Fonseca +13 more
wiley +1 more source
Targeting the epidermal growth factor receptor using IgM antibodies: toward next generation cancer immunotherapy. [PDF]
Front ImmunolSomboon K, Bond PJ, Samsudin F.
europepmc +1 more source
Oligoclonal IgM band patterns in multiple sclerosis: A two-center study
Francesco Di Masi +10 more
openalex +1 more source
IGM-Vis: Analyzing Intergalactic and Circumgalactic Medium Absorption\n Using Quasar Sightlines in a Cosmic Web Context [PDF]
, 2018 Joseph N. Burchett +5 more
openalex +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati +13 more
wiley +1 more source
Extended Duration of Anti-HEV IgM Seropositivity in Asymptomatic Blood Donors: Implications for Transfusion Safety. [PDF]
VirusesKempski J +6 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Children with primary immunodeficiency (PID) and secondary antibody deficiency (SAD) often require immunoglobulin replacement therapy due to low plasma immunoglobulin G (IgG) levels and recurrent infections. Existing pharmacokinetic models for immunoglobulin in PID patients predominantly focus on adults, with limited attention to ...
Iek Leng Cheng +4 more
wiley +1 more source
Impaired systemic antibody response against gut microbiota pathobionts in critical illness and susceptibility to nosocomial infections. [PDF]
Intensive Care Med ExpCho NA +6 more
europepmc +1 more source
Pre‐oviposition development of the brown anole (Anolis sagrei)
Developmental Dynamics, EarlyView.Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling +9 more
wiley +1 more source