Results 51 to 60 of about 54,905 (304)

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

open access: yesAdvanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo   +19 more
wiley   +1 more source

Quantifying Additive Manufacturing Vapor Plumes Using Laser‐Induced Breakdown Spectroscopy, Synchrotron X‐Ray Radiography and Simulations

open access: yesAdvanced Science, EarlyView.
This study presents a novel in situ laser‐induced breakdown spectroscopy system for monitoring metal vapors produced by the intense laser‐metal interactions in laser powder bed fusion additive manufacturing and laser welding. The insights from this new technique reveal changes in alloy compositions and provide the first in situ validation of multi ...
Anna C. M. Getley   +8 more
wiley   +1 more source

Influence of high ethane content on natural gas ignition

open access: yesRevista Ingenio, 2019
The effect of ethane on combustion and natural gas autoignition was studied in the present paper. Two fuel mixture of natural gas with high ethane content were considered, 75% CH4 – 25% C2H6 (mixture 1), and 50% CH4 – 50% C2H6 (mixture 2).
Hernando Alexander Yepes Tumay   +1 more
doaj   +1 more source

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

open access: yesAdvanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang   +10 more
wiley   +1 more source

Mathematical modelling of synthetic fuels ignition by local heat sources [PDF]

open access: yes, 2016
The numerical study is executed for polymethylmethacrylate ignition (typical model fuel for hybridrocket motors) by single particles in the shape of parallelepiped, polyhedron, and disk. The initial temperature ofheat source is varied in the range of 950-
Глушков, Дмитрий Олегович
core  

A mechanism for high-frequency oscillation in ramjet combustors and afterburners [PDF]

open access: yes, 1956
An experimental investigation was made of the behavior of a small two-dimensional combustion chamber, burning a uniform mixture of air and fuel vapor under conditions of high-frequency oscillation or screech.
Marble, Frank E., Rogers, Don E.
core   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Study of Optimum Blasting Condition to Lower the Blasting Vibration

open access: yesJournal of MMIJ, 2018
Because blasting is a quite efficient and economical excavation method, it has been widely applied to tunnel excavation especially in hard rock. However, this method is rarely used to the tunnel site close to residential houses due to its environmental ...
Keita IWANO   +3 more
doaj   +1 more source

Local Ignition in Carbon/Oxygen White Dwarfs -- I: One-zone Ignition and Spherical Shock Ignition of Detonations

open access: yes, 2005
The details of ignition of Type Ia supernovae remain fuzzy, despite the importance of this input for any large-scale model of the final explosion. Here, we begin a process of understanding the ignition of these hotspots by examining the burning of one ...
Desbordes D.   +4 more
core   +2 more sources

A study on schedule management for BIM projects in the construction industry [PDF]

open access: yes, 2018
There is an advance modelling tool that currently been pushed by the industry is BIM. BIM as known as Building Modelling Information is a computerized process that is used to design, understand and establish the key physical and functional characteristic
Ali, Roslinda   +2 more
core   +2 more sources

Home - About - Disclaimer - Privacy