Results 201 to 210 of about 488,008 (333)

Oleoylethanolamide regulates intestinal stem cell activity and villus size via PPARα signaling pathway

iMetaOmics, EarlyView.
First use of a natural swine model with lipid metabolism to directly link lipid differences to a quantifiable intestinal villus height phenotype. Identified the phospholipid‐derived oleoylethanolamide, rather than canonical fatty acids, as the endogenous primary ligand that activates peroxisome proliferator‐activated receptors α (PPARα) to enlarge ...
Qianqian Wang, Lanmei Yin, Zhaobin Wang, Jun Li, Xianglin Zeng, Qiye Wang, Jianzhong Li, Kang Xu, Huansheng Yang, Yulong Yin   +9 more
wiley   +1 more source

Evaluation of INR101, a PSMA-Targeted ¹⁸F PET Tracer, for suspected prostate cancer: A multicenter phase I/IIa trial with histopathologic confirmation. [PDF]

EJNMMI Res
Yang J, Wan W, Zhang J, Zhang N, Yang X, Wang W, Ma H, Xu Y, Fu Z, Wang X, Liu Y, Wang M, Liu F, Guo Y, Liu Y, Zhang X.   +15 more
europepmc   +1 more source

Effectiveness Test of Sidaguri Leaf Ethanol Extract Gel (Sida rhombifolia L.) on the Cealing of Degree IIA Burn in Male Rabbits

, 2023
Bazlina Adani, Gabena Indrayani Dalimunthe, Minda Sari Lubis, D. Elysa Putri Mambang   +3 more
openalex   +2 more sources

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

MDX-2001-101 study protocol: a phase I/IIa, multicenter, first-in-human, open-label clinical trial evaluating MDX2001 monotherapy in patients with advanced solid tumors. [PDF]

Future Oncol
Dumbrava E, Minchom A, Henry J, Johnson M, Sommerhalder D, Merchan J, Heist R, Cabanas EG, Cotreau M, Goenaga AL, Burzyn D, Makris L, Culm K, Abbadessa G.   +13 more
europepmc   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

Effects of acidosis and inorganic phosphate on Ca²⁺ sensitivity of young and older adult skeletal muscle fibers. [PDF]

Am J Physiol Cell Physiol
Teigen LE, Zepeda CS, Dobrzycki I, Hunter SK, Fitts RH, Sundberg CW.   +5 more
europepmc   +1 more source

Modeling Factors Associated With Diarrhea Caused by Cryptosporidium Species Using Machine Learning Methods

Journal of Clinical Laboratory Analysis, EarlyView.
This study applies machine learning methods, specifically Random Forest and Bagged CART, to classify Cryptosporidium spp. infections among children and identify key risk factors. The Bagged CART model demonstrated superior sensitivity and predictive performance, highlighting household crowding and water source as the most influential determinants of ...
Türkan Mutlu Yar, Zeynep Küçükakçali, Ülkü Karaman   +2 more
wiley   +1 more source

Mpox animal models: a comprehensive evaluation of susceptible species for pathogenesis studies and drug discovery. [PDF]

Emerg Microbes Infect
de La Vega MA, Xiii A, Woolsey C, Kobinger GP.   +3 more
europepmc   +1 more source

The Evaluation of Ecoprint Training for Female Inmates at The Class IIA Women’s Correctional Institution in Semarang

Dhian Saraswati, Wulan Sumekar, Titik Ekowati   +2 more
openalex   +1 more source