Results 81 to 90 of about 737 (163)

Characterization of IKAP localization in PNS WT and FD hESC-derived cultured neurons.

, 2015
Immunofluorescence confocal microscopy analysis was performed as shown in Fig 3. IKAP together with peripherin and Rab3a expression are shown within hESC derived neurons in WT (A-F) and FD (G-L) genetic backgrounds. Images B and H show the expression and
Miguel Weil (222465), Einat Aizenman (157691), Aviel Even (554750), Sharona Even-Ram (803379), Nibal Bashir (803380), Benjamim E. Reubinoff (803381), Gal Kantor (803376), Sharon Lefler (253080), Malkiel A. Cohen (253081), Yaniv Gil (132152), Channa Maayan (234102), Anastasya Birger (803377), David Cheishvili (554749), Tikva Turetsky (803378), Aharon Razin (554751)   +14 more
core   +1 more source

Localization of IKAP in hESC-derived PNS neurons in respect to vesicular neuronal markers SV2 and Rab3a.

, 2015
Confocal micrographs of hESC derived PNS neurons double-stained with Rabbit anti-hIKAP antibodies combined with either antibodies against synaptic vesicular markers, synaptic vesicle 2 (SV2) (A-G) or with Rab3a (H-J).
Miguel Weil (222465), Einat Aizenman (157691), Aviel Even (554750), Sharona Even-Ram (803379), Nibal Bashir (803380), Benjamim E. Reubinoff (803381), Gal Kantor (803376), Sharon Lefler (253080), Malkiel A. Cohen (253081), Yaniv Gil (132152), Channa Maayan (234102), Anastasya Birger (803377), David Cheishvili (554749), Tikva Turetsky (803378), Aharon Razin (554751)   +14 more
core   +1 more source

Familial Dysautonomia: Mechanisms and Models

Genetics and Molecular Biology
Hereditary Sensory and Autonomic Neuropathies (HSANs) compose a heterogeneous group of genetic disorders characterized by sensory and autonomic dysfunctions.
Paula Dietrich, Ioannis Dragatsis
doaj   +3 more sources

PENDAMPINGAN PENGEMBANGAN PRODUK UNGGULAN KAWASAN PERDESAAN PADA USAHA BERBASIS KOMUNITAS DESA CIBOGO

Dinamisia, 2018
Desa Cibogo merupakan salah satu desa yang ada dalam wilayah Kecamatan Cisauk, Kabupaten Tangerang. Desa Cibogo terletak di lokasi yang sangat strategis karena berdampingan dengan kawasan modern Bumi Serpong Damai dan stasiun kereta rel listrik Cisauk ...
Ambang Aries Yudanto, Taufik Raharjo, Roby S Ubed   +2 more
doaj   +1 more source

IKAP expression in WT and FD early and mature neurons.

, 2015
(A) RT-PCR analysis of the expression of IKBKAP showing WT (upper lane) and FD (mis-spliced, lower lane) mRNA isoforms at the stage of early neuronal precursors, early and mature neurons.
Miguel Weil (222465), Einat Aizenman (157691), Aviel Even (554750), Sharona Even-Ram (803379), Nibal Bashir (803380), Benjamim E. Reubinoff (803381), Gal Kantor (803376), Sharon Lefler (253080), Malkiel A. Cohen (253081), Yaniv Gil (132152), Channa Maayan (234102), Anastasya Birger (803377), David Cheishvili (554749), Tikva Turetsky (803378), Aharon Razin (554751)   +14 more
core   +1 more source

PENGARUH POLA ASUH ORANGTUA TERHADAP SIKAP SISWA DALAM PELAKSANAAN TATA TERTIB SEKOLAH (Studi Eks-post facto di Kelas VIII SMP Al Kautsar Bandar Lampung Tahun Pelajaran 2013/2014)

Insight: Jurnal Bimbingan dan Konseling, 2014
Penelitian ini bertujuan untuk mengetahui gambaran sikap terhadap pelaksanaan tata tertib sekolah siswa yang diasuh dengan pola asuh demokratis, otoriter, dan permisif serta untuk mengetahui perbedaan pengaruh pola asuh demokratis, otoriter, dan permisif
Fatwiasih Al Humaira, Dewi Justitia, Djunaedi Djunaedi   +2 more
doaj   +1 more source

Combined treatments with phosphatidylserine elevates IKAP protein level more efficiently than either drug alone.

, 2019
FD cells were treated for 5 days either with (A) 50 μg/ml PS or 10 μM kinetin (Kin) or the combination of both drugs, and (B) 50 μg/ml PS or 100 ng/ml TSA or the combination of both drugs. Upper panels: Western blotting of FD cell lysates after indicated
Maya Donyo (234098), Sivan Yannai (3594626), Jonathan Zonszain (3594617), Gil Ast (10995)   +3 more
core   +1 more source

Familial dysautonomia (FD) patients have reduced levels of the modified wobble nucleoside mcm5s2U in tRNA [PDF]

, 2014
Familial dysautonomia (FD) is a recessive neurodegenerative genetic disease. FD is caused by a mutation in the IKBKAP gene resulting in a splicing defect and reduced levels of full length IKAP protein.
Karlsborn, Tony,, Tukenmez, Hasan,, Byström, Anders,, Karlsborn, Tony, Chen, Changchun, Tükenmez, Hasan, Byström, Anders S.   +6 more
core   +1 more source

Pridopidine elevates IKAP protein level and affects acetylated α-tubulin levels and BDNF secretion in FD cells.

, 2019
(A-D) FD cells were treated with 0, 10, 100, 500, 1000, and 10,000 nM of pridopidine. Control treatment was done with vehicle only. (A) Western blotting of FD cell lysates with and without pridopidine treatment for 10 days.
Maya Donyo (234098), Sivan Yannai (3594626), Jonathan Zonszain (3594617), Gil Ast (10995)   +3 more
core   +1 more source

Caractérisation des rôles biologiques de la protéine IKAP et du complexe Elongator

, 2006
As the first step in the complex process of gene expression, the transcription of genes from DNA to RNA by RNA polymerase II is subject to a multiplicity of controls and is thereby the endpoint of multiple cell regulatory pathways. We focused here on the
Close, Pierre
core