Results 1 to 10 of about 673,523 (162)
Transcriptional elongation control in developmental gene expression, aging, and disease
Molecular Cell, 2023 SUMMARY The elongation stage of transcription by RNA polymerase II (Pol II) is central to the regulation of gene expression in response to developmental and environmental cues in metazoan.
Yuki Aoi, Ali Shilatifard
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Viral–Host Interactions That Control HIV-1 Transcriptional Elongation
Chemical Reviews, 2013 1. Summary Regulation of the pause and elongation by RNA polymerase (Pol) II is used widely by metazoans to attain the pattern of gene expression that is essential for optimal cell growth/renewal, differentiation and stress response.
Yuhua Xue, Qiang Zhou, Zichong Li
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Control of translation elongation in health and disease
Disease Models & Mechanisms, 2020 Regulation of protein synthesis makes a major contribution to post-transcriptional control pathways. During disease, or under stress, cells initiate processes to reprogramme protein synthesis and thus orchestrate the appropriate cellular response. Recent
John R. P. Knight +12 more
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The Plant Cell, 2021 Cotton, one of the most important crops in the world, produces natural fiber materials for the textile industry. WRKY transcription factors play important roles in plant development and stress responses.
Na-Na Wang +7 more
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Regulation of transcription elongation in response to osmostress. [PDF]
PLoS Genetics, 2017 Cells trigger massive changes in gene expression upon environmental fluctuations. The Hog1 stress-activated protein kinase (SAPK) is an important regulator of the transcriptional activation program that maximizes cell fitness when yeast cells are exposed
Andrea Silva +7 more
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Transcription elongation factor SII [PDF]
BioEssays, 2000 RNA chain elongation by RNA polymerase II (pol II) is a complex and regulated process which is coordinated with capping, splicing, and polyadenylation of the primary transcript. Numerous elongation factors that enable pol II to transcribe faster and/or more efficiently have been purified. SII is one such factor.
M, Wind, D, Reines
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A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans. [PDF]
PLoS Genetics, 2016 The elongation phase of transcription by RNA Polymerase II (Pol II) involves numerous events that are tightly coordinated, including RNA processing, histone modification, and chromatin remodeling.
Jeong H Ahn +3 more
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Functional specialization of transcription elongation factors [PDF]
The EMBO Journal, 2008 Elongation factors NusG and RfaH evolved from a common ancestor and utilize the same binding site on RNA polymerase (RNAP) to modulate transcription. However, although NusG associates with RNAP transcribing most Escherichia coli genes, RfaH regulates just a few operons containing ops, a DNA sequence that mediates RfaH recruitment. Here, we describe the
Georgiy A, Belogurov +4 more
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TRIM28 as a novel transcriptional elongation factor [PDF]
BMC Molecular Biology, 2015 TRIM28 is a multidomain protein with versatile functions in transcription and DNA repair. Recently it was shown that this factor plays unanticipated roles in transcriptional elongation. TRIM28 was shown to stabilize the pausing of RNA polymerase II (Pol II) close to the transcriptional start site in many unactivated genes, permitting Pol II ...
Heeyoun Bunch, Stuart K Calderwood
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Translational repression by a transcriptional elongation factor [PDF]
Genes & Development, 1997 One of the classical positive regulators of gene expression is bacteriophage λ N protein. N regulates the transcription of early phage genes by participating in the formation of a highly processive, terminator-resistant transcription complex and thereby stimulates the expression of genes lying downstream of transcriptional terminators. Also included in
H R, Wilson +4 more
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