Results 21 to 30 of about 106,553 (310)
The prefoldin complex regulates chromatin dynamics during transcription elongation. [PDF]
PLoS Genetics, 2013 Transcriptional elongation requires the concerted action of several factors that allow RNA polymerase II to advance through chromatin in a highly processive manner.
Gonzalo Millán-Zambrano +6 more
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FACT, a Factor that Facilitates Transcript Elongation through Nucleosomes [PDF]
Cell, 1998 The requirements for transcriptional activation by RNA polymerase II were examined using chromatin templates assembled in vitro and a transcription system composed of the human general transcription factors and RNA polymerase II. Activator-induced, energy-dependent chromatin remodeling promoted efficient preinitiation complex formation and ...
Orphanides, George +4 more
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Transcriptional termination enhances protein expression in human cells [PDF]
, 2009 Transcriptional termination of mammalian RNA polymerase II (Pol II) requires a poly(A) (pA) signal and, often, a downstream terminator sequence. Termination is triggered following recognition of the pA signal by Pol II and subsequent pre-mRNA cleavage ...
Proudfoot, Nicholas J +4 more
core +1 more source
Frontiers in Immunology, 2023 IntroductionBromodomain-containing Protein 4 (BRD4) is a transcriptional regulator which coordinates gene expression programs controlling cancer biology, inflammation, and fibrosis.
Morgan W. Mann +11 more
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Structure and Function of the Human Transcription Elongation Factor DSIF [PDF]
Journal of Biological Chemistry, 1999 5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) is a classic inhibitor of transcription elongation by RNA polymerase II (pol II). We have previously identified and purified a novel transcription elongation factor, termed DSIF (for DRB sensitivity-inducing factor), that makes transcription sensitive to DRB.
Yamaguchi, Y. +5 more
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Transcription elongation factor hSPT5 stimulates mRNA capping [PDF]
Genes & Development, 1999 RNA polymerase II nascent transcripts are capped during pausing before elongation. Here we report that hSPT5, the human homolog of yeast elongation factor SPT5, interacts directly with the capping enzyme. hSPT5 stimulated capping enzyme guanylylation and mRNA capping by severalfold.
Y, Wen, A J, Shatkin
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A conserved phosphorylation site regulates the transcriptional function of ETHYLENE-INSENSITIVE3-like1 in tomato [PDF]
, 2011 ETHYLENE-INSENSITIVE3/ETHYLENE-INSENSITIVE3-like (EIN3/EIL) transcription factors are important downstream components of the ethylene transduction pathway known to regulate the transcription of early ethylene-responsive genes in plants.
Z. Li +11 more
core +1 more source
System Analysis of MIRNAs in Maize Internode Elongation
Biomolecules, 2019 MicroRNAs (miRNAs), the post-transcriptional gene regulators, are known to play an important role in plant development. The identification of differentially expressed miRNAs could better help us understand the post-transcriptional regulation that occurs ...
Chuanxi Peng +7 more
doaj +1 more source
Reading of the non‐template DNA by transcription elongation factors [PDF]
Molecular Microbiology, 2018 SummaryUnlike transcription initiation and termination, which have easily discernable signals, such as promoters and terminators, elongation is regulated through a dynamic network involving RNA/DNA pause signals and states‐rather than sequence‐specific protein interactions. A report by Nedialkov et al.
Vladimir Svetlov, Evgeny Nudler
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Transcription elongation is finely tuned by dozens of regulatory factors
eLife, 2022 Understanding the complex network that regulates transcription elongation requires the quantitative analysis of RNA polymerase II (Pol II) activity in a wide variety of regulatory environments. We performed native elongating transcript sequencing (NET-seq) in 41 strains of Saccharomyces cerevisiae
Kate C Lachance +7 more
openaire +3 more sources