Results 21 to 30 of about 192,584 (302)

Ethylene-independent promotion of photomorphogenesis in the dark by cytokinin requires COP1 and the CDD complex [PDF]

, 2019
The transition of skotomorphogenesis to photomorphogenesis is induced by the perception of light, and is characterized by the inhibition of hypocotyl elongation and opening of cotyledons.
Cortleven, Anne, Ehret, Stephanie, Johansson, Henrik, Schmülling, Thomas   +3 more
core   +1 more source

Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]

, 2017
Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani, Bunnik, Evelien M, Le Roch, Karine G, Lee, Michael, Lu, Xueqing Maggie, Prudhomme, Jacques   +5 more
core   +1 more source

Transcription elongation factor hSPT5 stimulates mRNA capping [PDF]

Genes & Development, 1999
RNA polymerase II nascent transcripts are capped during pausing before elongation. Here we report that hSPT5, the human homolog of yeast elongation factor SPT5, interacts directly with the capping enzyme. hSPT5 stimulated capping enzyme guanylylation and mRNA capping by severalfold.
Y, Wen, A J, Shatkin
openaire   +2 more sources

Bromodomain-containing Protein 4 regulates innate inflammation via modulation of alternative splicing

Frontiers in Immunology, 2023
IntroductionBromodomain-containing Protein 4 (BRD4) is a transcriptional regulator which coordinates gene expression programs controlling cancer biology, inflammation, and fibrosis.
Morgan W. Mann, Yao Fu, Robert L. Gearhart, Xiaofang Xu, David S. Roberts, Yi Li, Jia Zhou, Ying Ge, Ying Ge, Ying Ge, Allan R. Brasier, Allan R. Brasier   +11 more
doaj   +1 more source

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat. [PDF]

, 2013
Human positive transcription elongation factor b (P-TEFb) phosphorylates RNA polymerase II and regulatory proteins to trigger elongation of many gene transcripts.
Alber, Tom, Bao, Katherine, Birnberg, Andrew, Chou, Seemay, Krogan, Nevan J, Schulze-Gahmen, Ursula, Upton, Heather, Zhou, Qiang   +7 more
core   +1 more source

FACT, a Factor that Facilitates Transcript Elongation through Nucleosomes [PDF]

Cell, 1998
The requirements for transcriptional activation by RNA polymerase II were examined using chromatin templates assembled in vitro and a transcription system composed of the human general transcription factors and RNA polymerase II. Activator-induced, energy-dependent chromatin remodeling promoted efficient preinitiation complex formation and ...
Orphanides, George, LeRoy, Gary, Chang, Chun-Hsiang, Luse, Donal S, Reinberg, Danny   +4 more
openaire   +2 more sources

Structure and Function of the Human Transcription Elongation Factor DSIF [PDF]

Journal of Biological Chemistry, 1999
5,6-Dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) is a classic inhibitor of transcription elongation by RNA polymerase II (pol II). We have previously identified and purified a novel transcription elongation factor, termed DSIF (for DRB sensitivity-inducing factor), that makes transcription sensitive to DRB.
Yamaguchi, Y., Wada, T., Watanabe, D., Takagi, T., Hasegawa, J., Handa, H.   +5 more
openaire   +2 more sources

System Analysis of MIRNAs in Maize Internode Elongation

Biomolecules, 2019
MicroRNAs (miRNAs), the post-transcriptional gene regulators, are known to play an important role in plant development. The identification of differentially expressed miRNAs could better help us understand the post-transcriptional regulation that occurs ...
Chuanxi Peng, Xing Wang, Tianyu Feng, Rui He, Mingcai Zhang, Zhaohu Li, Yuyi Zhou, Liusheng Duan   +7 more
doaj   +1 more source

A splicing-dependent transcriptional checkpoint associated with prespliceosome formation [PDF]

, 2014
There is good evidence for functional interactions between splicing and transcription in eukaryotes, but how and why these processes are coupled remain unknown.
Ahn, Aitken, Alexander, Alexander, Batsché, Bentley, Buratowski, Carrillo Oesterreich, Chapman, Chen, Cho, Cordin, Cramer, Damgaard, Das, David, de Almeida, Dönmez, Edgar, Egloff, Fong, Furger, Görnemann, Hirose, J. David Barrass, Jean D. Beggs, Ji, Kameoka, Keerthi T. Chathoth, Komarnitsky, Kornblihtt, Kornblihtt, Kosowski, Lacadie, Levine, Li, Lin, McCracken, McKay, Miller, Moore, Orphanides, Perriman, Perriman, Perriman, Perriman, Pleiss, Ruby, Schmidt, Schneider, Schroeder, Shao, Shaun Webb, Singh, Tardiff, Wahl, Wells, Witten, Xu, Xu, Yan, Zavanelli, Zhou   +62 more
core   +1 more source

Reading of the non‐template DNA by transcription elongation factors [PDF]

Molecular Microbiology, 2018
SummaryUnlike transcription initiation and termination, which have easily discernable signals, such as promoters and terminators, elongation is regulated through a dynamic network involving RNA/DNA pause signals and states‐rather than sequence‐specific protein interactions. A report by Nedialkov et al.
Vladimir Svetlov, Evgeny Nudler
openaire   +2 more sources