Results 31 to 40 of about 1,096,946 (288)
Frontiers in Immunology, 2022 Traumatic brain injury (TBI) is a devastating condition due to its long-term sequelae on neurological functions. Inflammatory responses after TBI are critical for injury expansion and repair.
Di Xie +7 more
semanticscholar +1 more source
The association between airway eosinophilic inflammation and IL-33 in stable non-atopic COPD
Respiratory Research, 2018 Background Interleukin(IL)-33 is an epithelial alarmin important for eosinophil maturation, activation and survival. The aim of this study was to examine the association between IL-33, its receptor expression and airway eosinophilic inflammation in non ...
Damian Tworek +8 more
doaj +1 more source
IL-33/sST2 axis in The Cardiovascular System: A Brief Review [PDF]
Trends in Pharmaceutical Sciences, 2020 IL-33 is a type of cytokine and a new member of the IL-1 family labeled as an alarmin, which is released under stressful settings. IL-33 is a biomechanically induced protein and is mainly produced by cardiac fibroblasts and is expressed by various cell ...
Negar Firouzabadi, Maryam Dashti
doaj +1 more source
Interleukin-33 contributes to both M1 and M2 chemokine marker expression in human macrophages [PDF]
, 2010 Background Interleukin-33 is a member of the IL-1 cytokine family whose functions are mediated and modulated by the ST2 receptor. IL-33-ST2 expression and interactions have been explored in mouse macrophages but little is known about the effect of IL-33 ...
Das, Anuk +7 more
core +5 more sources
Biotechnology & Biotechnological Equipment, 2018 IL-33 binding to IL1RL1 is involved in asthma. The data show that involvement of the IL33/IL1RL1 genes in asthma is biologically plausible. The objective of this study was to investigate the association of IL33 and IL1R1 gene polymorphisms and serum IL ...
Guangyang Zhang +4 more
doaj +1 more source
Structural Basis of IL-1 Family Cytokine Signaling
Frontiers in Immunology, 2019 Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and adaptive immune systems, mediating inflammation in response to a wide range of stimuli.
James K. Fields +6 more
doaj +1 more source
Frontiers in Medicine, 2021 Interleukin-33 (IL-33) is a nuclear factor mainly expressed in barrier epithelium, endothelial cells, and fibroblast reticular cells. Some inflammatory cells also express IL-33 under certain conditions.
Yuanji Dong, Jixin Zhong, Lingli Dong
doaj +1 more source
IL-33 ameliorates Alzheimer’s disease-like pathology and cognitive decline [PDF]
, 2016 Alzheimer’s disease (AD) is a devastating condition with no known effective treatment. AD is characterized by memory loss as well as impaired locomotor ability, reasoning, and judgment.
Chan, Ivy C. W. +10 more
core +1 more source
Serum sST2 levels predict severe exacerbation of asthma
Respiratory Research, 2018 Background Neutrophilic inflammation is associated with poorly controlled asthma. Serum levels of sST2, a soluble IL-33 receptor, increase in neutrophilic lung diseases. We hypothesized that high serum sST2 levels in stable asthmatics are a predictor for
Masato Watanabe +11 more
doaj +1 more source
The ST2/IL-33 Pathway in Adult and Paediatric Heart Disease and Transplantation
Biomedicines, 2023 ST2 is a member of interleukin 1 receptor family with soluble sST2 and transmembrane ST2L isoforms. The ligand of ST2 is IL-33, which determines the activation of numerous intracytoplasmic mediators following the binding with ST2L and IL-1RAcP, leading ...
Giacomina Brunetti +5 more
doaj +1 more source