Results 101 to 110 of about 1,058,742 (271)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The IL-36 subfamily is a recently described group of cytokines with pro-inflammatory behavior, comprising three agonists (α, β and γ), its receptor (R) and one antagonist (Ra).
José Martin Murrieta Coxca +7 more
doaj +1 more source
An analysis of IL-36 signature genes and individuals with IL1RL2 knockout mutations validates IL-36 as a psoriasis therapeutic target [PDF]
Satveer K. Mahil +12 more
openalex +1 more source
IL-36 s in the colorectal cancer: is interleukin 36 good or bad for the development of colorectal cancer? [PDF]
Feier Chen +7 more
openalex +1 more source
L’utilizzo degli animali nello sport – il d.lgs. 36/2021 le criticità di una normativa attesa e dovuta [PDF]
Tommaso Di Paolo, Martina Toniato
openalex +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Cut Elimination for a Logic with Induction and Co-induction [PDF]
Proof search has been used to specify a wide range of computation systems. In order to build a framework for reasoning about such specifications, we make use of a sequent calculus involving induction and co-induction.
Momigliano, Alberto, Tiu, Alwen
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Rifugiati o libertà? Le responsabilità dell’Europa nella crisi dei rifugiati siriani in Turchia. [PDF]
Le responsabilità dell'Europa nella crisi dei rifugiati siriani in ...
Cantelmo, MARIA CHIARA
core

