Results 71 to 80 of about 1,058,742 (271)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Who's In Who's Out: A Look at Access to Employer-based Retirement Plans and Participation in the States [PDF]

open access: yes, 2016
With the aging of the nation's population, a continuing decline in the availability of traditional pensions, and concerns about the future of Social Security, many workers in the United States worry that they won't have enough money set aside for their ...
Andrew Blevins   +3 more
core  

Pippo: An Italian Folklore Mystery of World War II

open access: yes, 2003
During the German occupation of Northern Italy (1943-45), the Italian populace lived under the grip of fear as Allied bombardments pummeled towns, Nazifascists raided villages looking for partisans, and food grew ever more scarce.
Perry, Alan R.
core   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

IL-36 signaling in keratinocytes controls early IL-23 production in psoriasis-like dermatitis

open access: yesLife Science Alliance, 2020
IL-36 signaling in keratinocytes is crucial for Aldara-induced psoriasis-like dermatitis by controlling IL-23/IL-17A/IL-22 production and neutrophil recruitment at the third day of treatment.
Jérémie D Goldstein   +6 more
doaj   +1 more source

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Interleukin-36 family as a novel regulator of inflammation in the barrier tissues

open access: yesМедицинская иммунология, 2020
The interleukin-36 (IL-36) family was discerned in the superfamily of interleukin-1 (IL-1) ten years ago. This family includes three isoforms of IL-36α, IL-36β, IL-36γ, which have pro-inflammatory activity and a specific receptor antagonist, IL-36ra ...
S. V. Sennikova, A. P. Toptygina
doaj   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian   +7 more
wiley   +1 more source

Se Doefel Daner [PDF]

open access: yes, 1981
When the Angles, Saxons and Jutes invaded England during the fifth century, they wiped out the native Celts both physically and linguistically. Except for place-names, only a half-dozen or so Celtic words entered Old English.
Brooke, Maxey
core   +1 more source

A step towards testing general relativity using weak gravitational lensing and redshift surveys [PDF]

open access: yes, 2009
Using the linear theory of perturbations in General Relativity, we express a set of consistency relations that can be observationally tested with current and future large scale structure surveys.
A. Cooney   +30 more
core   +2 more sources

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