Results 161 to 170 of about 447,090 (290)

IL-1β stimulates release of substance P (SP) and neurotensin (NT) and increases expression of their receptors on lamina propria macrophages (LPMS)

, 1998
Ignazio Castagliuolo, C Wang, GJ Previte, Asiya Pasha, Charalabos Pothoulakis   +4 more
openalex   +1 more source

ATP Acts as an Agonist to Promote Stimulus-Induced Secretion of IL-1β and IL-18 in Human Blood [PDF]

, 2000
David G. Perregaux, Pat McNiff, Ron Laliberte, Maryrose J. Conklyn, Christopher A. Gabel   +4 more
openalex   +1 more source

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

Molecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger, Dorin Bar‐Ziv, Harriet Kluger   +2 more
wiley   +1 more source

Comparison of Methods of Detecting IL-1β in the Blood of Alzheimer's Disease Subjects. [PDF]

Int J Mol Sci
Remnitz AD, Hadad R, Keane RW, Dietrich WD, de Rivero Vaccari JP.   +4 more
europepmc   +1 more source

FAS Engagement Induces the Maturation of Dendritic Cells (Dcs), the Release of Interleukin (Il)-1β, and the Production of Interferon γ in the Absence of IL-12 during Dc–T Cell Cognate Interaction [PDF]

, 2000
María Rescigno, Vincent Piguet, Barbara Valzasina, Suzanne Lens, Rudolf H. Zubler, Lars E. French, Vincent Kindler, Jürg Tschopp, Paola Ricciardi‐Castagnoli   +8 more
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

P62 inhibits IL-1β release during <i>Salmonella</i> Typhimurium infection of macrophages. [PDF]

Front Cell Infect Microbiol
Hos NJ, Fischer J, Murthy AMV, Hejazi Z, Krönke M, Hos D, Robinson N.   +6 more
europepmc   +1 more source

Lipoxin A4 Inhibits IL-1β-Induced IL-6, IL-8, and Matrix Metalloproteinase-3 Production in Human Synovial Fibroblasts and Enhances Synthesis of Tissue Inhibitors of Metalloproteinases [PDF]

, 2000
Snežna Sodin‐Šemrl, Brunella Taddeo, Daniel Tseng, John Varga, Stefano Fiore   +4 more
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

IL-1β stimulates ADAMTS9 expression and contributes to preterm prelabor rupture of membranes. [PDF]

Cell Commun Signal
Cao J, Wang Y, Lin Q, Wang S, Shen Y, Zhang L, Li W, Chen L, Liu C, Yao S, Shuai L, Chen X, Li Z, Chang Y.   +13 more
europepmc   +1 more source