Results 141 to 150 of about 6,778,674 (329)

Circadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance The molecular clock provides an anticipatory mechanism, allowing organisms to prepare and respond to daily changes in the external environment.
James O. Early, D. Menon, C. Wyse, Mariana P. Cervantes-Silva, Z. Zaslona, R. Carroll, E. Pålsson-McDermott, Stefano Angiari, D. Ryan, Sarah E. Corcoran, George A. Timmons, Sarah S. Geiger, Darren J. Fitzpatrick, Daniel J. O'Connell, R. Xavier, K. Hokamp, L. O'Neill, A. Curtis   +17 more
semanticscholar   +1 more source

Additional file 1: of IL-1β-induced modulation of gene expression profile in human dermal fibroblasts: the effects of Thai herbal Sahatsatara formula, piperine and gallic acid possessing antioxidant properties

, 2017
The overview of microarray analysis work flow (Figure S1) and the list of human housekeeping genes matching with gene array in microarray BeadChip (Table S1). (DOCX 32Â kb)
Thamsermsang, Onusa, Akarasereenont, Pravit, Laohapand, Tawee, Panich, Uraiwan   +3 more
openaire   +1 more source

Development and validation of ELISAs for the quantitation of interleukin (IL)-1β, IL-6, IL-8 and IL-10 in ovine plasma

, 2020
There is growing evidence that inflammation underpins many common diseases. Inflammatory/immunomodulatory/immune mediators, such as cytokines, are key modulators of inflammation and mediate both immune cell recruitment and complex intracellular ...
Simonova, G, Tung, JP, Passmore, MR, Fraser, JF, See Hoe, LE, Bouquet, M, Boon, AC   +6 more
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration

Nature Communications, 2018
Spinal cord injury leads to a massive response of innate immune cells in non-regenerating mammals, but also in successfully regenerating zebrafish. However, the role of the immune response in successful regeneration is poorly defined.
Themistoklis M. Tsarouchas, Daniel Wehner, L. Cavone, Tahimina Munir, Marcus Keatinge, Marvin Lambertus, Anna Underhill, T. Barrett, Elias Kassapis, Nikolay V. Ogryzko, Yi Feng, T. V. van Ham, T. Becker, C. G. Becker   +13 more
semanticscholar   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

A Critical Role of the IL-1β-IL-1R Signaling Pathway in Skin Inflammation and Psoriasis Pathogenesis

Journal of Investigative Dermatology, 2018
IL-1 signaling pathway has been shown to play a critical role in the pathogenesis of chronic, autoinflammatory skin diseases such as psoriasis. However, the exact cellular and molecular mechanisms have not been fully understood.
Yi-Hua Cai, F. Xue, C. Quan, Minye Qu, Na Liu, Yuan Zhang, Chris Fleming, Xiao-Ling Hu, Huang-Ge Zhang, R. Weichselbaum, Yang-Xin Fu, David Tieri, E. Rouchka, Jie Zheng, Jun Yan   +14 more
semanticscholar   +1 more source

Additional file 3: of IL-1β-induced modulation of gene expression profile in human dermal fibroblasts: the effects of Thai herbal Sahatsatara formula, piperine and gallic acid possessing antioxidant properties

, 2017
The list of significant gene alterations; up-regulation (Table S1) and down-regulation (Table S2) (DOCX 26 kb)
Onusa Thamsermsang, Akarasereenont, Pravit, Tawee Laohapand, Uraiwan Panich   +3 more
openaire   +1 more source

IL-1β induced a decrease in TER values.

, 2016
In cells treated with 10% FBS (open circles) and 2% FBS in the presence (closed circles) or absence (closed squares) of IL-1β (50 pM) for the indicated time periods, the barrier properties were monitored by measuring TER.
Taku Kitanaka (3350276), Nanako Kitanaka (3350285), Tadayoshi Konno (3350282), Ryo Mamiya (3350291), Takanori Narita (25602), Ken Okabayashi (820737), Hisashi Tsuchiya (3350279), Hiroshi Sugiya (412101), Rei Nakano (820735), Shinichi Namba (3350288)   +9 more
core   +1 more source

Double-walled carbon nanotubes trigger IL-1β release in human monocytes through Nlrp3 inflammasome activation [PDF]

, 2012
Because of their outstanding physical properties, carbon nanotubes (CNTs) are promising new materials in the field of nanotechnology. It is therefore imperative to assess their adverse effects on human health.
Dardenne, Christophe, Meunier, Etienne, Bernard Pipy, David Olagnier, José Bernad, Agnès Coste, Authier, Hélène, Emmanuel Flahaut, Béraud, Maryse, Bernad, José, Flahaut, Emmanuel, Etienne Meunier, Maryse Béraud, Pipy, Bernard, Lise Lefèvre, Christophe Dardenne, Coste, Agnès, Hélène Authier, Olagnier, David, Lefèvre, Lise   +19 more
core   +1 more source