Results 271 to 280 of about 15,170,590 (380)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Early Postpartum IL-10 and IL-37 Concentrations in Women with Gestational Diabetes Mellitus. [PDF]

Med Sci Monit
Gorczyca K, Kimber-Trojnar Ż, Koziol MM, Leszczyńska-Gorzelak B.   +3 more
europepmc   +1 more source

Claudio Vacanti, Guerra per la Sicilia e guerra della Sicilia. Il ruolo delle città siciliane nel primo conflitto Romano-Punico (=Storia Politica Costituzionale e Militare del Mondo Antico 6), Napoli, Jovene editore, 2012, 251 pp., 10 figs. [ISBN: 978-88- 243-2165-5]

, 2014
María Morán Ruiz
openalex   +1 more source

Change of C/A at the SNP -592 of human IL-10 gene increase serum IL-10 levels in patients with cervical lesions and cervical cancer

, 2013
TORRES-POVEDA KIRVIS, BAHENA-ROM�N MARGARITA, LAGUNAS-MART�NEZ ALFREDO, Karina Delgado-Romero, CANT� DAVID, GARC�A-CARRANC� ALEJANDRO, M.J. Izquierdo Vicente   +6 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

IL-10- and IL-13-Biased T Cell Responses to SARS-CoV-2 Vaccination in Diabetes. [PDF]

Eur J Immunol
Jones EM, Sourij C, Stradner M, Schlenke P, Sereban N, Moser O, Quinlan R, Short CE, Harris BHL, Fertleman M, Taylor GP, Oliver N, Sourij H, Dominguez-Villar M.   +13 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Protective Effects of Gallic Acid in LPS-Induced Lung Injury via Modulation of Oxidative Stress: AKT1/NRF2 and IL-10 Signaling. [PDF]

J Biochem Mol Toxicol
Unal O, Asci H, Selcuk E, Milletsever A, Tepebasi MY, Asci Y, Gulal A, Ozmen O.   +7 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Prolonged Release of IL-10 From Enzyme-Mediated Poly-l-(Tyrosine-co-Phenylalanine) Nanocrystals Enhances Stability and Modulates Inflammatory Responses. [PDF]

Biopolymers
Landa-Tencle F, Hernández-Valencia CG, Guzmán-Lagunes F, Montiel C, Cuellar-Entenza Y, Guerrero-Sánchez C, Stumpf S, Hoeppener S, Schubert US, Zamudio-Cuevas Y, Sánchez-Sánchez R, Gimeno M.   +11 more
europepmc   +1 more source