Results 61 to 70 of about 13,602,078 (332)

Central Nervous System Parasitosis and Neuroinflammation Ameliorated by Systemic IL-10 Administration in Trypanosoma brucei-Infected Mice [PDF]

, 2015
Peer reviewedPublisher ...
A Chakraborty, AE Chernoff, B Namangala, Barbara Bradley, CA Hunter, CA Hunter, DN Amin, E Di Santo, FW Jennings, J Rodgers, Jayne Raper, Jean Rodgers, Jeremy M. Sternberg, JM Sternberg, JM Sternberg, K Asadullah, L MacLean, L MacLean, L MacLean, M Guilliams, P Kobbe, Peter G. E. Kennedy, PG Kennedy, PG Kennedy, RD Huhn, U Frevert, W Masocha   +26 more
core   +11 more sources

Elevated interleukin-10, -22, -24, and -26 in serum samples of children with infectious mononucleosis [PDF]

Journal of Medical Biochemistry
Background: Infectious mononucleosis (IM) is an infectious disease with different stages of onset, and the pathogenesis of IM remains unclear. This study aimed to investigate the levels of interleukin (IL)-10 family cytokines IL-10, -22, -24, and -26 in ...
Li Dalei, Mao Kangwei, Luo Peiliang, Zheng Ziqiang, Liu Jiangyan, Zhang Chenxi, Gu Siyu, Zhang Rui, Sun Jun, Wang Juan   +9 more
doaj   +1 more source

Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signalling

Gut, 2019
Objective Macrophage interleukin (IL)-10 signalling plays a critical role in the maintenance of a regulatory phenotype that prevents the development of IBD. We have previously found that anti-tumour necrosis factor (TNF) monoclonal antibodies act through
P. Koelink, F. Bloemendaal, Bofeng Li, L. Westera, E. Vogels, M. van Roest, Anouk K. Gloudemans, A. B. van 't Wout, H. Korf, S. Vermeire, A. T. Te Velde, C. Ponsioen, G. D’Haens, J. Verbeek, T. Geiger, M. Wildenberg, G. R. van den Brink   +16 more
semanticscholar   +1 more source

Interleukin-10 containing normal human serum inhibits granzyme B release but not perforin release from alloreactive and EBV-specific T cell clones [PDF]

, 2007
Interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor, has pleiotropic effects in immunoregulation and inflammation. It is capable of inhibiting synthesis of pro-inflammatory cytokines like interferon γ (IFNγ), IL-2, IL-3,
Hideya Sato, Hitoshi Okazaki, Kenji Tadokoro, Masahiro Satake, Motoko Nishimura   +4 more
core   +2 more sources

Apoptosis in the lungs of pigs infected with porcine reproductive and respiratory syndrome virus and associations with the production of apoptogenic cytokines [PDF]

, 2003
International audienceApoptosis was studied in the lungs of pigs during an infection with a European strain of porcine reproductive and respiratory syndrome virus (PRRSV) and it was examined if cytokines were involved in the induction of apoptosis ...
Labarque, Geoffrey, Nauwynck, Hans, Pensaert, Maurice, Van Gucht, Steven, Van Reeth, Kristien   +4 more
core   +3 more sources

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

The Role of IL-10 in Malaria: A Double Edged Sword

Frontiers in Immunology, 2019
IL-10 produced by CD4+ T cells suppresses inflammation by inhibiting T cell functions and the upstream activities of antigen presenting cells (APCs). IL-10 was first identified in Th2 cells, but has since been described in IFNγ-producing Tbet+ Th1, FoxP3+
R. Kumar, Susanna S. Ng, C. Engwerda
semanticscholar   +1 more source

Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model [PDF]

, 2019
Background: Campylobacter jejuni infections constitute serious threats to human health with increasing prevalences worldwide. Our knowledge regarding the molecular mechanisms underlying host-pathogen interactions is still limited.
Backert, Steffen, Bereswill, Stefan, Boehm, Manja, Escher, Ulrike, Heimesaat, Markus M., Mousavi, Soraya, Schmidt, Anna-Maria, Tegtmeyer, Nicole   +7 more
core   +4 more sources

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

The Correlation between Interleukin-10 Serum with Bacterial Index in Multidrug Therapy-treated Leprosy Patients

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016
Background: Immune respons disturbance oftenly found in leprosy patient, mainly in various T cell subset and cytokine immune system arranger. Interleukin-10 produced by Th 2 cell, Th3 cell, monocyte, dendritic cell, eosinophil, mast cell, and ...
Eva Krishna Sutedja, Jono Hadi Agusni, Hartati Purbo Dharmadji   +2 more
doaj   +1 more source