Results 81 to 90 of about 2,038,009 (287)

Induction of human IL-10-producing neutrophils by LPS-stimulated Treg cells and IL-10 [PDF]

Mucosal Immunology, 2016
Recent evidence has revealed an unsuspected suppressive role played by neutrophils during microbial infections. An especially intriguing aspect of this role is the ability of neutrophils to produce interleukin (IL)-10 following interaction with lipopolysaccharide (LPS)-stimulated regulatory T (Treg) cells. The present study demonstrates that generation
N, Lewkowicz, M P, Mycko, P, Przygodzka, H, Ćwiklińska, M, Cichalewska, M, Matysiak, K, Selmaj, P, Lewkowicz   +7 more
openaire   +2 more sources

RETRACTED: Rhodomyrtus tomentosa (Aiton) Hassk. (haramonting) protects against allethrin-exposed pulmo damage in rats: mechanistic interleukins

Frontiers in Pharmacology
Inhaling Allethrin (C19H26O3) may induce oxidative stress in lung cells by causing the formation of free radi-cals. Interleukins (IL) are a group of secreted cytokines or proteins and signaling molecules initially produced as an immune response by ...
Putri Cahaya Situmorang, Syafruddin Ilyas, Rony Abdi Syahputra, Alexander Patera Nugraha, Mimmy Sari Syah Putri, Cheryl Grace Pratiwi Rumahorbo   +5 more
doaj   +1 more source

Fungal Chitin Dampens Inflammation through IL-10 Induction Mediated by NOD2 and TLR9 Activation [PDF]

, 2014
Funding: JW and NARG thank the Wellcome Trust (080088, 086827, 075470), The Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology (097377) and the European Union ALLFUN (FP7/2007 2013, HEALTH-2010-260338) for funding. MGN was supported
Biedermann, Tilo, Brown, Alistair J P, Brown, Gordon D, Gow, Neil A R, Kanneganti, Thirumala-Devi, Köberle, Martin, Lenardon, Megan D, MacCallum, Donna M, Malireddi, R K Subbarao, Netea, Mihai G, Schaller, Martin, Vautier, Simon, Wagener, Jeanette   +12 more
core   +4 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Impact of IL-10 and IL-12B single nucleotide polymorphisms on circulating cytokine level in development of Hashimoto's thyroiditis

Biotechnology & Biotechnological Equipment, 2016
Hashimoto's thyroiditis (HT) is an organ-specific, mainly Th1 autoimmune disorder. New evidence has accumulated for involvement of Treg-produced cytokines.
Julieta Gerenova, Irena Manolova, Spaska Stanilova   +2 more
doaj   +1 more source

Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection. [PDF]

, 1994
Leishmania major are intramacrophage parasites whose eradication requires the induction of T helper 1 (Th1) effector cells capable of activating macrophages to a microbicidal state.
Locksley, RM, Reiner, SL, Stowring, L, Wang, ZE, Zheng, S   +4 more
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

UNDERSTANDING THE NEUROINFLAMMATORY RESPONSE FOLLOWING CONCUSSION TO DEVELOP TREATMENT STRATEGIES

Frontiers in Cellular Neuroscience, 2012
Mild traumatic brain injuries (mTBI) have been associated with long-term cognitive deficits relating to trauma-induced neurodegeneration. These long-term deficits include impaired memory and attention, changes in executive function, emotional instability
Zachary Robert Patterson, Matthew R Holahan   +1 more
doaj   +1 more source

Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model [PDF]

, 2019
Background: Campylobacter jejuni infections constitute serious threats to human health with increasing prevalences worldwide. Our knowledge regarding the molecular mechanisms underlying host-pathogen interactions is still limited.
Backert, Steffen, Bereswill, Stefan, Boehm, Manja, Escher, Ulrike, Heimesaat, Markus M., Mousavi, Soraya, Schmidt, Anna-Maria, Tegtmeyer, Nicole   +7 more
core   +4 more sources

Suppression of antigen presentation by IL-10 [PDF]

Current Opinion in Immunology, 2015
Regulated antigen presentation to immune cells determines the effectiveness of an immune response. IL-10 is an immunosuppressive cytokine that regulates immune responses by inhibiting the ability of APCs to present antigens to T cells in a variety of ways.
Sharad K, Mittal, Paul A, Roche
openaire   +2 more sources