Results 1 to 10 of about 1,832,666 (293)

The relationship between serum levels of interleukin-2 and IL-8 with circulating microRNA-10b in patients with COVID-19 [PDF]

open access: yesIranian Journal of Immunology, 2021
Background: The role of cytokine storm in the immunopathogenesis of coronavirus disease 2019 (COVID-19) has been implicated. Objective: To determine the association of microRNA (miRNA)-10b and serum levels of IL-2 and IL-8 in patients with COVID-19 ...
Zahra Bagheri-Hosseinabadi   +4 more
doaj   +1 more source

Clinical Sports Medicine

open access: yesDeutsche Zeitschrift für Sportmedizin, 2023
Purpose: The COVID-19 pandemic affects society on a global scale in many ways. In Germany, various social and leisure facilities such as schools, sports clubs and gyms had to be closed due to lockdowns.
Kalski L   +7 more
doaj   +1 more source

Factors Associated with Tuberculosis Relapses Development

open access: yesТуберкулез и болезни лёгких, 2022
The objective: to identify socio-demographic, clinical and laboratory factors associated with tuberculosis recurrence.Subjects and Methods. Clinical and laboratory data of 208 TB patients treated at the National Scientific Center for Phthisiopulmonology ...
A. A. Abilbayeva   +5 more
doaj   +1 more source

In silico data mining of large-scale databases for the virtual screening of human interleukin-2 inhibitors

open access: yesActa Pharmaceutica, 2021
Interleukin-2 (IL-2) is involved in the activation and differentiation of T-helper cells. Uncontrolled activated T cells play a key role in the pathophysiology by stimulating inflammation and autoimmune diseases like arthritis, psoriasis and Crohn’s ...
Halim Sobia Ahsan   +4 more
doaj   +1 more source

Immune Mechanism of Tumor Cell Lysate Combined with IL-2 Preventing Melanoma and Inhibiting Tumor Growth

open access: yesZhongliu Fangzhi Yanjiu, 2021
Objective To investigate the preventive and inhibitory effects of tumor cell lysate(TCL) combined with IL-2 on melanoma and the potential immune mechanism. Methods The B16F10 melanoma TCL cell were prepared using an ultrasonic disruptor.
SI Yiran   +6 more
doaj   +1 more source

Regulation of T cell differentiation by the AP-1 transcription factor JunB

open access: yesImmunological Medicine, 2021
JunB, a component of the activator protein-1 (AP-1) transcription factor, is known to exhibit an important role in bone formation and bone marrow cell proliferation. During T helper type 2 (Th2) cell differentiation, JunB contributes to the regulation of
Takaharu Katagiri   +3 more
doaj   +1 more source

The cellular markers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immune response [PDF]

open access: yesCellR4, 2022
Objective: The peculiarity of immune response during and after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is of special interest as this may contribute to the development of an efficient diagnostic approach.
E. Kldiashvili   +2 more
doaj   +1 more source

Evaluation Of Cytokines Changes In Patients Infected With Giardia lamblia In Comparison With Healthy Subjects [PDF]

open access: yesپیاورد سلامت, 2012
Background and Aim: Human Giardisis infection is caused by the flagellate protozoa. Giardia lamblia, which lives in the small intestine, causing damage and may also cause gastrointestinal symptoms.
Mitra Zarebavani   +3 more
doaj   +1 more source

Interleukine-2 serum level in breast cancer patients [PDF]

open access: yesCaspian Journal of Internal Medicine, 2023
Background: Breast cancer is a form of cancer that typically affects females. In general, cancer is caused by an imbalance between oncogene and supressor gene factors, including immunity factors against cancer cells. This study aims to compare the levels
Tutik Harjianti   +4 more
doaj  

Potent immunomodulatory effects of an anti-CEA-IL-2 immunocytokine on tumor therapy and effects of stereotactic radiation

open access: yesOncoImmunology, 2020
While anti-CEA antibodies have no direct effect on CEA-positive tumors, they can be used to direct potent anti-tumor effects as an antibody-IL-2 fusion protein (immunocytokine, ICK), and at the same time reduce the toxicity of IL-2 as a single agent ...
Maciej Kujawski   +14 more
doaj   +1 more source

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