Results 21 to 30 of about 116,073,120 (283)
DYNAMICS OF IL-2 PLASMA LEVELS IN HIV PATIENTS WITH CONSIDERING DRUGS RESISTANCE
Инфекция и иммунитет, 2018 Interleukin-2 (IL-2) is one of the most important cytokines involved in the regulation of innate and adaptive immunity. Its main immunological function is to regulate a specific (antigen-dependent) immune response by stimulating proliferation and ...
E. S. Eliseeva +4 more
doaj +1 more source
Journal of Immunotoxicology, 2020 Arsenic (As) readily crosses the placenta and exposure of the fetus may cause adverse consequences later in life, including immunomodulation. In the current study, the question was asked how the immune repertoire might respond in postnatal life when ...
Mainak Chakraborty, Moumita Bhaumik
doaj +1 more source
Acta Pharmaceutica, 2021 Interleukin-2 (IL-2) is involved in the activation and differentiation of T-helper cells. Uncontrolled activated T cells play a key role in the pathophysiology by stimulating inflammation and autoimmune diseases like arthritis, psoriasis and Crohn’s ...
Halim Sobia Ahsan +4 more
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The IL-2 – IL-2 receptor pathway: Key to understanding multiple sclerosis
Journal of Translational Autoimmunity, 2021 The development, progression, diagnosis and treatment of autoimmune diseases, such as multiple sclerosis (MS), are convoluted processes which remain incompletely understood. Multiple studies demonstrated that the interleukin (IL)-2 - IL-2 receptor (IL-2R) pathway plays a pivotal role within these processes.
Daphne Peerlings +2 more
openaire +4 more sources
Regulation of T cell differentiation by the AP-1 transcription factor JunB
Immunological Medicine, 2021 JunB, a component of the activator protein-1 (AP-1) transcription factor, is known to exhibit an important role in bone formation and bone marrow cell proliferation. During T helper type 2 (Th2) cell differentiation, JunB contributes to the regulation of
Takaharu Katagiri +3 more
doaj +1 more source
Nigella sativa oil protects against cadmium-induced intestinal toxicity via promotion of anti-inflammatory mechanisms, mucin expression and microbiota integrity [PDF]
Avicenna Journal of Phytomedicine, 2022 Objective: This study examined the protective effects of Nigella sativa oil (NSO) on cadmium (Cd)-induced alterations affecting gut morphology and microbiota composition, as well as the involvement of mucus glycoprotein (MUC2) and immuno-inflammatory ...
Akinleye Akinrinde +2 more
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IL-1β-induced activation of ERK1/2.
, 2021 (a, b) Time-dependent changes of ERK1/2 phosphorylation. Western blotting for the levels of phosphorylated ERK1/2 (p-ERK1/2) and total ERK1/2 (t-ERK1/2) in dermal fibroblasts treated with IL-1β (100 pM) (a) and relative levels of [p-ERK1/2]/[t-ERK1/2] in
Taku Kitanaka (3350276) +9 more
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Бюллетень сибирской медицины, 2015 Very little research is devoted to the study of communication systemic immunological changes and local immunological changes in the tissue of the thyroid in autoimmune thyrophaties.
T. V. Saprina +10 more
doaj +1 more source
Correlation of regulatory T cells in chronic lymphocytic leukemia characterized by high-affinity CD25 expression with serum IL-2 values, IGVH mutational status, Rai stage, and therapeutic lines [PDF]
Romanian Medical Journal, 2020 The impact of the importance of regulatory T cells (Treg) in chronic lymphocytic leukemia (CLL) is still controversial and no consensus has been reached on whether the effects generated by these cells are positive or negative in terms of tumor ...
Georgiana Ene +4 more
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Cytoplasmic tail of IL-13Ralpha2 regulates IL-4 signal transduction
, 2009 IL (interleukin)-4 and IL-13 are key cytokines in the pathogenesis of allergic inflammatory disease. IL-4 and IL-13 share many functional properties as a result of their utilization of a common receptor complex comprising IL-13Ralpha1 (IL-13 receptor ...
Donna E. Davies +13 more
core +1 more source