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The cellular markers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immune response [PDF]

open access: yesCellR4, 2022
Objective: The peculiarity of immune response during and after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is of special interest as this may contribute to the development of an efficient diagnostic approach.
E. Kldiashvili   +2 more
doaj   +1 more source

Clinical Sports Medicine

open access: yesDeutsche Zeitschrift für Sportmedizin, 2023
Purpose: The COVID-19 pandemic affects society on a global scale in many ways. In Germany, various social and leisure facilities such as schools, sports clubs and gyms had to be closed due to lockdowns.
Kalski L   +7 more
doaj   +1 more source

Vai trò của hạt từ phủ kháng thể CD3/CD28 và IL-2 lên sự tăng sinh tế bào đơn nhân máu ngoại vi người (PBMC)

open access: yesTạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ, 2022
Liệu pháp miễn dịch được coi là một phương pháp đầy hứa hẹn trong điều trị ung thư. Tế bào miễn dịch của bệnh nhân được phân lập, cảm ứng tăng sinh, biến đổi thành các tế bào chức năng khác nhau và sau đó được đưa trở lại người bệnh. Các tế bào miễn dịch
Phùng Thị Việt Anh   +2 more
doaj   +1 more source

Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor [PDF]

open access: yesOpen Biology, 2012
Certain disulfide bonds present in leucocyte membrane proteins are labile and can be reduced in inflammation. This can cause structural changes that result in downstream functional effects, for example, in integrin activation.
Clive Metcalfe   +2 more
doaj   +1 more source

Proinflammatory Cytokines and Its Correlation with Liver Injury

open access: yesThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2022
Background: A persistent infection of hepatitis B virus (HBV) can cause liver cirrhosis and hepatocarcinoma even though the virus itself is non-cytopathic and does not cause cell injury.
Tri Nugraha Susilawati   +2 more
doaj   +1 more source

The relationship between serum levels of interleukin-2 and IL-8 with circulating microRNA-10b in patients with COVID-19 [PDF]

open access: yesIranian Journal of Immunology, 2021
Background: The role of cytokine storm in the immunopathogenesis of coronavirus disease 2019 (COVID-19) has been implicated. Objective: To determine the association of microRNA (miRNA)-10b and serum levels of IL-2 and IL-8 in patients with COVID-19 ...
Zahra Bagheri-Hosseinabadi   +4 more
doaj   +1 more source

Local therapy with an engineered oncolytic adenovirus enables antitumor response in non-injected melanoma tumors in mice treated with aPD-1

open access: yesOncoImmunology, 2022
Intratumoral immunotherapies are entering clinical use but concerns remain regarding their effects on non-injected tumors. Here, we studied the impact of local treatment with an adenovirus coding for TNFa and IL-2 on systemic antitumor response in ...
Dafne C. A. Quixabeira   +11 more
doaj   +1 more source

Evaluation Of Cytokines Changes In Patients Infected With Giardia lamblia In Comparison With Healthy Subjects [PDF]

open access: yesپیاورد سلامت, 2012
Background and Aim: Human Giardisis infection is caused by the flagellate protozoa. Giardia lamblia, which lives in the small intestine, causing damage and may also cause gastrointestinal symptoms.
Mitra Zarebavani   +3 more
doaj   +1 more source

TCB2, a new anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity

open access: yesOncoImmunology, 2020
IL-2 is a pleiotropic cytokine that plays an essential role in the survival, expansion, and function of CD8 T cells, regulatory T cells (Tregs), and natural killer (NK) cells.
Jun-Young Lee   +8 more
doaj   +1 more source

A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy

open access: yesOncoImmunology, 2020
Anti-CD20 treatment represents a therapeutic benefit for patients with B-cell lymphomas, although more efficient therapies are needed for refractory or relapsing patients. Among them, the combination of anti-CD20 and IL-2 that induces T cell response has
Ana Victoria Casadesús   +8 more
doaj   +1 more source

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