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The cellular markers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immune response [PDF]
Objective: The peculiarity of immune response during and after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is of special interest as this may contribute to the development of an efficient diagnostic approach.
E. Kldiashvili +2 more
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Purpose: The COVID-19 pandemic affects society on a global scale in many ways. In Germany, various social and leisure facilities such as schools, sports clubs and gyms had to be closed due to lockdowns.
Kalski L +7 more
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Liệu pháp miễn dịch được coi là một phương pháp đầy hứa hẹn trong điều trị ung thư. Tế bào miễn dịch của bệnh nhân được phân lập, cảm ứng tăng sinh, biến đổi thành các tế bào chức năng khác nhau và sau đó được đưa trở lại người bệnh. Các tế bào miễn dịch
Phùng Thị Việt Anh +2 more
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Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor [PDF]
Certain disulfide bonds present in leucocyte membrane proteins are labile and can be reduced in inflammation. This can cause structural changes that result in downstream functional effects, for example, in integrin activation.
Clive Metcalfe +2 more
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Proinflammatory Cytokines and Its Correlation with Liver Injury
Background: A persistent infection of hepatitis B virus (HBV) can cause liver cirrhosis and hepatocarcinoma even though the virus itself is non-cytopathic and does not cause cell injury.
Tri Nugraha Susilawati +2 more
doaj +1 more source
The relationship between serum levels of interleukin-2 and IL-8 with circulating microRNA-10b in patients with COVID-19 [PDF]
Background: The role of cytokine storm in the immunopathogenesis of coronavirus disease 2019 (COVID-19) has been implicated. Objective: To determine the association of microRNA (miRNA)-10b and serum levels of IL-2 and IL-8 in patients with COVID-19 ...
Zahra Bagheri-Hosseinabadi +4 more
doaj +1 more source
Intratumoral immunotherapies are entering clinical use but concerns remain regarding their effects on non-injected tumors. Here, we studied the impact of local treatment with an adenovirus coding for TNFa and IL-2 on systemic antitumor response in ...
Dafne C. A. Quixabeira +11 more
doaj +1 more source
Evaluation Of Cytokines Changes In Patients Infected With Giardia lamblia In Comparison With Healthy Subjects [PDF]
Background and Aim: Human Giardisis infection is caused by the flagellate protozoa. Giardia lamblia, which lives in the small intestine, causing damage and may also cause gastrointestinal symptoms.
Mitra Zarebavani +3 more
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IL-2 is a pleiotropic cytokine that plays an essential role in the survival, expansion, and function of CD8 T cells, regulatory T cells (Tregs), and natural killer (NK) cells.
Jun-Young Lee +8 more
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A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy
Anti-CD20 treatment represents a therapeutic benefit for patients with B-cell lymphomas, although more efficient therapies are needed for refractory or relapsing patients. Among them, the combination of anti-CD20 and IL-2 that induces T cell response has
Ana Victoria Casadesús +8 more
doaj +1 more source

