Results 191 to 200 of about 116,073,120 (283)

D24. Financial Toxicity Associated With Cleft Palate Repair: A Survey of Family Financial Well-being

Plastic and Reconstructive Surgery, Global Open
Sophia Allison, BA, Hannah Soltani, BA, Emily Chwa, BS, Rachel Donaldson, BS, Arun Gosain, MD   +4 more
doaj   +1 more source

Bypassing the cytokine sink: IL-2-independent IL-2 receptor signaling

Molecular Therapy, 2023
openaire   +2 more sources

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Double activation and low IL-2 manufacturing protocol increase expansion of healthy and patient-derived CAR-Tregs. [PDF]

Mol Ther Adv
Ugolini A, Miceli A, Bercher-Brayer C, Cesarano S, Camisa B, Carulli P, Monti P, Ramirez GA, Bonomi E, Rudilosso L, Dagna L, Cesana D, Greco R, Ciceri F, Bonini C, Doglio M.   +15 more
europepmc   +1 more source

Unraveling the Structure of IL-2 [PDF]

Science, 1992
openaire   +2 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Effects of TNF-α, IL-1β and IL-2 on regulatory T cells in children with idiopathic nephrotic syndrome. [PDF]

Front Pediatr
Ni FF, Jia SL, Li CR, Gao XJ.
europepmc   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Regulatory T cells sabotage anti-tumor γδ T cells by creating IL-2-deficient environments. [PDF]

J Exp Med
Blanco-Domínguez R, Vaz-Pinto AM, Barros L, Lopes N, Henriques-Alves B, Carreira M, Labão-Almeida C, Ribot JC, Bernardes GJL, Silva-Santos B, Mensurado S.   +10 more
europepmc   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source