Results 201 to 210 of about 25,065,433 (389)

Interleukin 2 (IL 2) administered in vivo: influence of IL 2 route and timing on T cell growth. [PDF]

open access: bronze, 1985
Martin A. Cheever   +3 more
openalex   +1 more source

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes

open access: yesScience, 2018
Jonathan T. Sockolosky   +17 more
semanticscholar   +1 more source

miRNA‐29 regulates epidermal and mesenchymal functions in skin repair

open access: yesFEBS Letters, EarlyView.
miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan   +10 more
wiley   +1 more source

Defective production of and response to IL-2 in acute human falciparum malaria. [PDF]

open access: bronze, 1988
M Ho   +5 more
openalex   +1 more source

Early signaling defects in human T cells anergized by T cell presentation of autoantigen. [PDF]

open access: yes, 1992
Major histocompatibility complex class II-positive human T cell clones are nontraditional antigen-presenting cells (APCs) that are able to simultaneously present and respond to peptide or degraded antigen, but are unable to process intact protein ...
Freeman, GJ   +4 more
core  

Spot‐14 and its paralog Spot‐14R regulate expression of metabolic and thermogenic pathway genes in murine brown and beige adipocytes

open access: yesFEBS Letters, EarlyView.
Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez   +3 more
wiley   +1 more source

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism

open access: yesNature Network Boston, 2018
E. Trotta   +13 more
semanticscholar   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

open access: yesFEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring   +6 more
wiley   +1 more source

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