Results 211 to 220 of about 25,065,433 (389)

B cell stimulatory factor 1 (IL-4) enhances the development of cytotoxic T cells from Lyt-2+ resting murine T lymphocytes. [PDF]

, 1988
Guido Trenn, Hajime Takayama, Jane Hu‐Li, W E Paul, M V Sitkovsky   +4 more
openalex   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Efecto de la recuperación nutricia sobre la concentración de Interleucina-2 en niños con desnutrición grave

Archivos Latinoamericanos de Nutrición
El niño con desnutrición grave tiene una disfunción de la respuesta inmune que puede aumentar de manera significativa la morbilidad y la mortalidad por infecciones.
Edgar Vásquez-Garibay, Katja Stein, Concepción Méndez-Estrada, Elías Pérez-Becerra, Enrique Romero-Velarde, Isabel Ibarra Gutiérrez, Miguel Ángel Ortiz Ortega, Trinidad García Iglesias   +7 more
doaj  

Possible association between IL-2 receptors and class I HLA molecules on T cells. [PDF]

, 1988
M Sharon, James R. Gnarra, Michal Baniyash, Warren J. Leonard   +3 more
openalex   +1 more source

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

Structure-function relationships for the IL 2-receptor system. I. Localization of a receptor binding site on IL 2. [PDF]

, 1986
Li-Mei Kuo, R J Robb
openalex   +1 more source

Cytoplasmic delivery of antibodies through grafting a functional single complementarity‐determining region loop

FEBS Letters, EarlyView.
We achieved cytoplasmic delivery of non‐cell‐penetrating IgGs by grafting a single functional complementarity‐determining region 1 (CDR1) from the light chain variable region (VL) of the cell‐internalizable 3D8 antibody. The engineered IgG acquired cell‐penetrating ability while maintaining antigen affinity, highlighting CDR1 grafting as a promising ...
Yerin Jeon, Juho Choi, Youngin Roh, Eunbin Lee, Luigie Villamante, Myung‐Hee Kwon   +5 more
wiley   +1 more source

Treatment of a murine B cell lymphoma with monoclonal antibodies and IL 2. [PDF]

, 1987
Neil L. Berinstein, Ronald Levy
openalex   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Two regions within the human IL-2 gene promoter are important for inducible IL-2 expression. [PDF]

, 1988
Tom Williams, Leonard M. Eisenberg, Jeanne E. Burlein, Chad Norris, S Pancer, Di Yao, Sibylle Bürger, Malek Kamoun, J A Kant   +8 more
openalex   +1 more source