Results 221 to 230 of about 25,065,433 (389)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
INDUCTION OF IL-2 RECEPTOR EXPRESSION IN VIVO RESPONSE TO ALLOGENEIC CELLS
, 1987 Richard A. Kroczek +4 more
openalex +1 more source
Generation and characterization of IL-2-activated bone marrow cells as a potent graft vs tumor effector in transplantation. [PDF]
, 1989 R Agah +3 more
openalex +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Antigenic stimulation regulates the expression of IL 2 receptors in a cytolytic T lymphocyte clone. [PDF]
, 1985 John W. Lowenthal +4 more
openalex +1 more source
IL-2: The First Effective Immunotherapy for Human Cancer
Journal of Immunology, 2014 S. Rosenberg
semanticscholar +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Role of interleukin 1 in early T cell development: Lyt-2-L3T4- thymocytes bind and respond in vitro to recombinant IL 1. [PDF]
, 1986 Rawleigh Howe +2 more
openalex +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Infection and Drug ResistanceWenhui Guo,1,* Xiang Lian,2,* Hong Li,2 Lushun Jiang,1 Yingsha Chen,3 Ping Shen,1 Wei Yu1 1State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative ...
Guo W +6 more
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