Results 271 to 280 of about 1,832,666 (293)

Tumour vaccines expressing IL-2, CD80, and IL-2 plus CD80 gene

International Journal of Oncology, 1997
Experiments were designed to investigate immunogenicity and therapeutic efficacy of tumour vaccines constructed by transfection of poorly immunogenic murine sarcoma Mc12 with synergistic CD80 and IL-2 genes. Immunization/challenge experiments demonstrated that both, IL-2(+) and IL-2(+) plus CD80(+) live cell vaccines can exert an immunizing stimulus ...
J, Bubenik, P, Rossner, D, Bubenikova, J, Simova, M, Indrova, E, Sloncova   +5 more
openaire   +2 more sources

Interleukin 2 (IL-2) activity during tumor growth: IL-2 production kinetics, absorption of and responses to exogenous IL-2

Cellular Immunology, 1984
A temporal study assessed the relationship between fibrosarcoma growth and immunologic encumbrance due to the inability of BALB/c mouse splenocytes to elaborate the lymphokine Interleukin 2 (IL-2). Nylon-wool fractionation and antiserum treatments suggested the existence of a mildly nylon-wool-adherent, anti-Lyt 2-sensitive tumor-induced suppressor T ...
Burger, C J, Elgert, K D, Farrar, W L
openaire   +2 more sources

Contra-IL 2; a suppressor lymphokine that inhibits IL 2 activity.

The Journal of Immunology, 1986
Abstract Suppressive activity of culture supernatant of AS-9 (AS-9 CS), a T cell hybridoma line that was derived from fusion of BW5147 thymoma and splenic T cells of anti-lymphocyte serum-treated C3H mice, was analyzed. AS-9 CS inhibited allogeneic cytotoxic T lymphocyte (CTL) generation as well as T cell proliferation to alloantigens ...
T, Maki, S, Satomi, M, Gotoh, A P, Monaco   +3 more
openaire   +2 more sources

Cleanup on IL-2

Science Signaling
Prostaglandins in the tumor microenvironment block IL-2–induced expansion of killer T cells.
openaire   +2 more sources

Leu-enkephalin induced by IL-2 administration mediates analgesic effect of IL-2

NeuroReport, 2000
Interleukin-2 (IL-2) was found to have an analgesic effect in both central and peripheral nervous systems. This effect is related to opioid receptors and mediated mainly by IL-2 directly binding to opioid receptors. Using radioimmunoassay, the content of Leu-enkephalin (LEK) in some nuclei were measured at intervals after the injection of IL-2 into the
C L, Jiang, Z D, You, C L, Lu, D, Xu, A J, Wang, Y X, Wang, X Y, Liu   +6 more
openaire   +2 more sources

???????????? ?????????????????????????? ???????????????????? ????????????????????????-2 (IL-2 ) ????????????????, ?????????????????????? ?????????????? ???????????????????? ?????????????? ?? ???????????????? ?????????????? ???? ???????????? ?????????????????????????? ?? ??????-???? ???????????????? ???????? IL-2

2019
???? ???????????? ???????????????????????? ?????????????????? ?????????????? ??????, ?????????????????????????? W. Studier et al. ?????? ???????????????????? ?????????? ?? ???????????????? ??????????????, ?????????????? ?????????????????????? ?? ???????????? ?? ???????????????????????????????? ???????????????????????? ????????-???? ???????????????? ????
openaire   +1 more source

IL-2

Science-Business eXchange, 2008
  +5 more sources

Tumor Immunotherapy by IL-2 and IL-2 Gene Transfected Cells

1996
Tumortherapy is based on a variety of treatment modalities. Directly operating cytoreductive approaches are designed to work either locally like surgery or radiotherapy, or systemically like cytotoxic drugs. Other ways of treatment are going to exploit the interaction of tumor and host.
Lindemann, Albrecht, Rosenthal, Felicia M., Mackensen, Andreas, Veelken, Hendrik, Kulmburg, Peter, Lahn, Michael, Mertelsmann, Roland   +6 more
openaire   +2 more sources

Immunomodulatory activity of liposomal IL-2 (Lip-IL-2) and “Pegilated” IL-2 (PEG-IL-2) in mice

Cytokine, 1991
E. Kedar, Y. Rutkowski, E. Braun, N. Emanuel, Y. Barenholz   +4 more
openaire   +1 more source

IL-2

2001
Katherine A. Fitzgerald, Luke A.J. O'Neill, Andy J.H. Gearing, Robin E. Callard   +3 more
openaire   +1 more source