Results 21 to 30 of about 1,832,666 (293)

Prognostic value of inflammatory cytokine levels, clinical efficacy, and prognosis of the hybrid artificial liver support system in chronic liver failure treatment [PDF]

open access: yesJournal of Medical Biochemistry
Background: This study aimed to evaluate the effectiveness and safety of the hybrid artificial liver support system (HALSS) in patients with chronic liver failure (CLF). It also sought to analyze the inflammatory response and patient prognosis.
Liu Lihua   +4 more
doaj   +1 more source

FEATURES OF INTERLEUKIN-2 AND INTERLEUKIN-4 PRODUCTION AND RECEPTION IN AUTOIMMUNE THYROID DISORDERS

open access: yesМедицинская иммунология, 2014
. The aim of this study was to evaluate some immunopathogenic features of autoimmune thyropathies (autoimmune thyroiditis and Graves’ disease), in terms of IL-2 and IL-4 production and expression of specific surface receptors on blood lymphocytes.
T. V. Saprina
doaj   +1 more source

Exposure of 1800 MHz Radiofrequency with SAR 1,6 W/kg Caused a Significant Reduction in CD4+ T Cells and Release of Cytokines In-Vitro [PDF]

open access: yesIranian Journal of Immunology, 2020
Background: Although there have been many studies investigating the effects of electromagnetic fields on humans cells and tissues, the effects of radiofrequency electromagnetic fields exposure on the cells of the immune system are still controversial ...
Maimun Zulhaidah Arthamin   +6 more
doaj   +1 more source

PROGNOSIS FOR PREDISPOSAL TO DEVELOPMENT OF VIRAL HEPATITIS C BASED ON G-308A TNFА, T-330G IL-2, С-590Т IL-4, С-703Т IL-5, AND C-592A IL-10 GENE POLYMORPHISMS

open access: yesМедицинская иммунология, 2014
. The main objective of this work was to identify allelic variants of cytokine genes at the polymorphic positions of G-308A TNFА, T-330G IL-2, С-590Т IL-4, С-703Т IL-5, and C-592A IL-10, and to assess their contribution to predisposition and resistance ...
V. V. Avdoshina   +6 more
doaj   +1 more source

TCB2, a new anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity

open access: yesOncoImmunology, 2020
IL-2 is a pleiotropic cytokine that plays an essential role in the survival, expansion, and function of CD8 T cells, regulatory T cells (Tregs), and natural killer (NK) cells.
Jun-Young Lee   +8 more
doaj   +1 more source

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar   +8 more
wiley   +1 more source

IMMUNOLOGICAL INDEXES AND CYTOKINE PROFILE IN THE CHILDREN DURING INFECTIOUS MONONUCLEOSIS CAUSED BY EPSTEIN-BARR VIRUS

open access: yesМедицинская иммунология, 2014
. Sixty-nine children (5 to 14 years old) with infectious mononucleosis caused by EBV were observed in acute phase and during recovery period. The indexes under study did evaluate cell-mediated and humoral immunity, levels of spontaneous and mitogen ...
L. M. Kurtasova, A. E. Golovanova
doaj   +1 more source

A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy

open access: yesOncoImmunology, 2020
Anti-CD20 treatment represents a therapeutic benefit for patients with B-cell lymphomas, although more efficient therapies are needed for refractory or relapsing patients. Among them, the combination of anti-CD20 and IL-2 that induces T cell response has
Ana Victoria Casadesús   +8 more
doaj   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis   +9 more
wiley   +1 more source

POSSIBLE MECHANISMS OF STIMULATORY EFFECTS OF MESENCHYMAL STROMAL CELLS UPON T CELL RECOVERY DURING CHEMOTHERAPY-INDUCED LYMPHOPENIA

open access: yesМедицинская иммунология, 2014
The aim of present work was to evaluate the effect of mesenchymal stromal cells (MSCs) from lymphoma patients on the in vitro and in vivo homeostatic proliferation of lymphocytes.
E. V. Batorov   +8 more
doaj   +1 more source

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