Results 121 to 130 of about 1,307,311 (352)

Induction in Pancreas Transplantation: T-cell Depletion Versus IL-2 Receptor Blockade. [PDF]

Transplant Direct, 2022
Aziz F, Parajuli S, Kaufman D, Odorico J, Mandelbrot D.   +4 more
europepmc   +1 more source

Effect of rapamycin on the expression of the IL-2 receptor (CD25)

Clinical and Experimental Immunology, 1996
SUMMARY The immunosuppressive macrolide rapamycin inhibits cytokine-driven proliferation of lymphocytes, acting at a later stage of T lymphocyte activation than the related compound FK506 or cyclosporin, which block IL-2 transcription.
Ryffel B, Woerly G, Brooks N
openaire   +4 more sources

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Helicobacter pylori Induces IL-33 Production and Recruits ST-2 to Lipid Rafts to Exacerbate Inflammation

Cells, 2019
Helicobacter pylori colonizes human gastric epithelial cells and contributes to the development of several gastrointestinal disorders. Interleukin (IL)-33 is involved in various immune responses, with reported proinflammatory and anti-inflammatory ...
Chia-Jung Kuo, Chun-Ya Chen, Horng-Ren Lo, Chun-Lung Feng, Hui-Yu Wu, Mei-Zi Huang, Tung-Nan Liao, Yu-An Chen, Chih-Ho Lai   +8 more
doaj   +1 more source

SUSD2 suppresses CD8⁺ T cell antitumor immunity by targeting IL-2 receptor signaling. [PDF]

Nat Immunol, 2022
Zhao B, Gong W, Ma A, Chen J, Velegraki M, Dong H, Liu Z, Wang L, Okimoto T, Jones DM, Lei YL, Long M, Oestreich KJ, Ma Q, Xin G, Carbone DP, He K, Li Z, Wen H.   +18 more
europepmc   +1 more source

Mechanisms of human T cell response to mitogens: IL 2 induces IL 2 receptor expression and proliferation but not IL 2 synthesis in PHA-stimulated T cells. [PDF]

, 1985
D Katzen, E B Chu, C Terhost, Donald Y.M. Leung, Marianne L Gesner, Richard A. Miller, Raif S. Geha   +6 more
openalex   +1 more source

The Effects Of 5-Ht4 Receptor Agonists On Interleukin-10 Knockout Mice [PDF]

, 2018
Recent studies have demonstrated that activation of the 5-HT4 receptors in the colonic mucosa can have healing and protective actions in experimental models of colitis.
Mylie, Quentin
core   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

IL-2 receptor engineering enhances regulatory T cell function suppressed by calcineurin inhibitor. [PDF]

Am J Transplant, 2022
Hirai T, Lin PY, Ramos TL, Simonetta F, Su LL, Picton LK, Baker J, Lohmeyer JK, Garcia KC, Negrin RS.   +9 more
europepmc   +1 more source

The beta-chain of the IL-2 receptor (p70) is tyrosine-phosphorylated on YT and HUT-102B2 cells. [PDF]

, 1989
M Sharon, James R. Gnarra, Warren J. Leonard   +2 more
openalex   +1 more source