Az interleukin-15 receptor molekuláris kölcsönhatásainak vizsgálata humán sejtvonalakon = Investigation of molecular interactions of interleukin-15 receptor on human cell lines [PDF]
, 2008 Az IL-15 citokin fontos szerepet játszik a T sejtek működésében és homeosztázisában. Receptora felépítésében a citokin-specifikus alfa lánc és az IL-2R felépítésében is részt vevő béta és gamma alegység vesz részt.
Dóczy-Bodnár, Andrea +2 more
core
Interleukin‐2 (IL‐2) Receptor α, β and γ Subunit Expression as a Function of B‐Cell Lineage Ontogeny: the Use of IL‐2‐PE664Glu to Characterize Internalization via IL‐2 Receptor Subunits [PDF]
, 1997 Ida Steinberger +3 more
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Interleukin 2 and stimulator lymphoblastoid cells will induce human thymocytes to bind and kill K562 targets. [PDF]
, 1982 Human thymocytes cultured in the presence of IL-2 and an irradiated B cell line became cytotoxic to K562 target cells. Thymocytes cultured alone or with only IL-2 exhibited almost no killing, but thymocytes cultured in the presence of stimulator cells ...
Golub, SH, Sidell, N, Torten, M
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Soluble IL-2 Receptor in Dermatomyositis: Its Associations with Skin Ulcers and Disease Activity. [PDF]
Mediators Inflamm, 2020 He L +6 more
europepmc +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Animal Production: Indonesian Journal of Animal Production, 2010 Interleukin-8 (IL-8) receptor gene is response to bacterial invasion, endothelial and epithelial cells by release the chemokine interleukin-8 (IL-8). IL-8 mediates neutrophil function, allowing neutrophils to resolve bacterial infections by migrating ...
A Winaya, ID Rahayu
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist. [PDF]
Nat Commun, 2020 Parisi G +20 more
europepmc +1 more source