Results 171 to 180 of about 1,313,952 (350)
Structure-function relationships for the IL 2-receptor system. II. Localization of an IL 2 binding site on high and low affinity receptors. [PDF]
, 1986 Li-Mei Kuo, C M Rusk, R J Robb
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Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Production of a T cell hybridoma that expresses the T cell receptor gamma/delta heterodimer. [PDF]
, 1987 We have produced a T cell hybridoma line by fusion of an IL-2-dependent, long-term T cell receptor (TCR) gamma/delta+ Thy-1+, bone marrow-derived, dendritic epidermal cell line to the BW5147 tumor line.
Bluestone, JA +5 more
core
Comparison of the expression of IL 2 receptors by human T and B cells: induction by the polyclonal mitogens, phorbol myristate acetate, and anti-mu antibody. [PDF]
, 1985 Takeshi Suzuki, Max D. Cooper
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Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Animal Production: Indonesian Journal of Animal Production, 2010 Interleukin-8 (IL-8) receptor gene is response to bacterial invasion, endothelial and epithelial cells by release the chemokine interleukin-8 (IL-8). IL-8 mediates neutrophil function, allowing neutrophils to resolve bacterial infections by migrating ...
A Winaya, ID Rahayu
doaj
Dupilumab efficacy in uncontrolled, moderate-to-severe asthma with self-reported chronic rhinosinusitis [PDF]
, 2019 BACKGROUND: Dupilumab, a fully human monoclonal antibody, blocks the shared receptor component for IL-4 and IL-13 signaling, key drivers of type 2 inflammation.
Castro, Mario, et al,, Maspero, Jorge F
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Immature, double negative (CD4-,CD8-) rat thymocytes do not express IL-2 receptors. [PDF]
, 1988 László Takács +6 more
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Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source