Results 171 to 180 of about 2,340,150 (306)

Utilization of the beta and gamma chains of the IL‐2 receptor by the novel cytokine IL‐15.

EMBO Journal, 1994
Judith G. Giril, M. Ahdieh, J. Eisenman, K. Shanebeck, K. Grabstein, S. Kumaki, A. Namen, L. Park, D. Cosman, Dirk M. Anderson   +9 more
semanticscholar   +1 more source

INDUCTION OF IL-2 RECEPTOR EXPRESSION IN VIVO RESPONSE TO ALLOGENEIC CELLS

, 1987
Richard A. Kroczek, C D Black, Jacques Barbet, Linette J. Edison, Ethan M. Shevach   +4 more
openalex   +1 more source

Immature, double negative (CD4-,CD8-) rat thymocytes do not express IL-2 receptors. [PDF]

, 1988
László Takács, F W Ruscetti, Ernest Kovacs, Beatriz Rocha, Stefan Brocke, T Diamantstein, Bonnie J. Mathieson   +6 more
openalex   +1 more source

IL-2 Receptor β-Dependent STAT5 Activation Is Required for the Development of Foxp3+ Regulatory T Cells1

Journal of Immunology, 2007
M. Burchill, Jianying Yang, C. Vogtenhuber, B. Blazar, M. Farrar   +4 more
semanticscholar   +1 more source

Binding Selectivity Analysis from Alchemical Receptor Hopping and Swapping Free Energy Calculations [PDF]

arXiv
We present receptor hopping and receptor swapping free energy estimation protocols based on the Alchemical Transfer Method (ATM) to model the binding selectivity of a set of ligands to two arbitrary receptors. The receptor hopping protocol, where a ligand is alchemically transferred from one receptor to another in one simulation, directly yields the ...
arxiv  

Stages of T cell activation: continued antigen dependence of IL 2-producing cells after IL 2 receptor expression. [PDF]

, 1986
Richard A. Miller, Marta Rozans, A. Ythier, Terry B. Strom   +3 more
openalex   +1 more source

The Cytokine Receptor IL-7Rα Impairs IL-2 Receptor Signaling and Constrains the In Vitro Differentiation of Foxp3⁺ Treg Cells. [PDF]

iScience, 2020
Waickman AT, Keller HR, Kim TH, Luckey MA, Tai X, Hong C, Molina-París C, Walsh STR, Park JH.   +8 more
europepmc   +1 more source

Persistent IL-2 Receptor Signaling by IL-2/CD25 Fusion Protein Controls Diabetes in NOD Mice by Multiple Mechanisms. [PDF]

Diabetes, 2020
Ward NC, Lui JB, Hernandez R, Yu L, Struthers M, Xie J, Santos Savio A, Dwyer CJ, Hsiung S, Yu A, Malek TR.   +10 more
europepmc   +1 more source

A novel engineered IL-21 receptor arms T-cell receptor-engineered T cells (TCR-T cells) against hepatocellular carcinoma

Signal Transduction and Targeted Therapy
Strategies to improve T cell therapy efficacy in solid tumors such as hepatocellular carcinoma (HCC) are urgently needed. The common cytokine receptor γ chain (γc) family cytokines such as IL-2, IL-7, IL-15 and IL-21 play fundamental roles in T cell ...
Wei Zhu, Zhiming Zhang, Jinzhang Chen, Xiaolan Chen, Lei Huang, Xiaoyong Zhang, Xuan Huang, Na Ma, Weikang Xu, Xuan Yi, Xinyu Lu, Xin Fu, Siwei Li, Guoheng Mo, Yiyue Wang, Guosheng Yuan, Mengya Zang, Qi Li, Xiaotao Jiang, Yajing He, Sha Wu, Yukai He, Yongyin Li, Jinlin Hou   +23 more
doaj   +1 more source

Clinical Application Value of High-Frequency Ultrasound Combined with Detection of Serum High Mobility Group Box 1, Soluble IL-2 Receptor, and Thyroglobulin Antibody in Diagnosing Thyroid Cancer.

J Healthc Eng, 2022
Li N, Zhang J, Meng X, Yao W.
europepmc   +1 more source