Results 321 to 330 of about 1,313,952 (350)

IL 2 receptor induction on human T lymphocytes: role for IL 2 and monocytes.

The Journal of Immunology, 1985
Abstract In this report we studied the requirements for the activation and proliferation of highly purified human T lymphocytes. Purified T cells incubated for 3 days with PHA neither proliferate nor express IL 2 receptors as detected by FACS analysis with the use of anti-Tac antibodies.
H, Wakasugi, J, Bertoglio, T, Tursz, D, Fradelizi   +3 more
openaire   +2 more sources

The murine IL 2 receptor. III. Cellular requirements for the induction of IL 2 receptor expression on T cell subpopulations.

The Journal of Immunology, 1985
Abstract The accessory cell requirements for the induction of the IL 2 receptor by the lectin Con A on murine T cell subsets were directly assayed with anti-IL 2 receptor monoclonal antibodies. Substantial levels of IL 2 receptor expression were induced on T lymphocytes of the MHC class I-restricted, suppressor/cytotoxic phenotype (L3T4-,
T R, Malek, J A, Schmidt, E M, Shevach
openaire   +2 more sources

IL-2-PE40 is cytotoxic for activated T lymphocytes expressing IL-2 receptors.

The Journal of Immunology, 1988
Abstract IL-2-PE40 is a chimeric molecule in which IL-2 is attached to the amino end of modified Pseudomonas exotoxin molecule lacking cell recognition domain. This molecule was extremely toxic for Con A-stimulated spleen cells from mice. Moreover, IL-2-PE40 has suppressive effect against Ag-activated cells; it inhibits the generation of
M, Ogata, H, Lorberboum-Galski, D, FitzGerald, I, Pastan   +3 more
openaire   +2 more sources

Cloning of the γ Chain of the Human IL-2 Receptor

Science, 1992
A third subunit, the γ chain, of the human interleukin-2 receptor (IL-2R) was identified, and a complementary DNA clone encoding this member of the cytokine receptor family was isolated. The γ chain is necessary for the formation of the high- and intermediate-affinity receptors, which consist of αβγ heterotrimers and βγ heterodimers, respectively.
Kiyoshi Ohtani, Hiroshi Munakata, Hironobu Asao, Naoto Ishii, Toshikazu Takeshita, Masataka Nakamura, Nobuyuki Tanaka, Satoru Kumaki, Kazuo Sugamura   +8 more
openaire   +3 more sources

Soluble IL‐2 receptors in acute and subacute encephalitis

Annals of Neurology, 1987
AbstractElevated levels of soluble interleukin‐2 receptors were present in the serum from patients with acute primary and postinfectious encephalitis and subacute sclerosing panencephalitis. In addition, soluble interleukin‐2 receptors were detected in the cerebrospinal fluid from patients with acute primary encephalitis.
D L Nelson, P Lebon, Gérard Ponsot, Arthuis M, L. Matsuguchi, B Boutin   +5 more
openaire   +2 more sources

Structural Studies of T200 Glycoprotein and the Il-2 Receptor

Journal of Receptor Research, 1987
Immunological analysis of the cell surface of hematopoietic cells has led to the identification of many different cell membrane molecules, some of which have well-defined functions as receptors. In general, however, the role of most lymphocyte cell surface molecules remains ill-defined even in cases in which antibody inhibition studies have given some ...
S. Ralph, D. Shackelford, M. Thomas, Ian S. Trowbridge   +3 more
openaire   +3 more sources

Variations in serum soluble IL‐2 receptor concentration

Pediatric Allergy and Immunology, 1994
Soluble interleukin‐2 receptor (sIL‐2R) concentrations were measured in the sera of 18 healthy adult volunteers, 40 healthy children aged 5 months ‐ 16 years 8 months and cord blood from 10 babies, using two commercially available ELISA kits (T‐cell Sciences and Serotec).
Jane Warner, A. C. Jones, Jill A. Warner, C. R. Besley   +3 more
openaire   +3 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

T cells expressing IL-2 receptor in migraine.

Acta neurologica, 1991
We studied a group of migraine patients for circulating immune complexes, lymphocyte subpopulations, IgG4 and anti-IgG antibodies, before, after 4 hours and after 72 hours a specific challenge test. We found an increased incidence of circulating immune complexes. Total T cells showed a marked increase after challenge test.
openaire   +2 more sources

Critical care management of chimeric antigen receptor T‐cell therapy recipients

Ca-A Cancer Journal for Clinicians, 2022
Alexander Shimabukuro-vornhagen, Victoria Metaxa, Elie Azoulay   +2 more
exaly