Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Axial-flow pump design digital computer program [PDF]
FORTRAN program for computerized design of axial flow pump by blade element ...
Kavanagh, P., Miller, M. J.
core +1 more source
High Serum IL-31 Concentration Is Associated with Itch among Renal Transplant Recipients. [PDF]
Krajewski PK +8 more
europepmc +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Three-dimensional finite-element elastic analysis of a thermally cycled single-edge wedge geometry specimen [PDF]
An elastic stress analysis was performed on a wedge specimen (prismatic bar with single-wedge cross section) subjected to thermal cycles in fluidized beds.
Bizon, P. T. +4 more
core +1 more source
Enigmatic Role of IL-31 in the Itch and Inflammation of Vernal Keratoconjunctivitis. [PDF]
Okamoto M +4 more
europepmc +1 more source
IL-31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH. [PDF]
Xu J +20 more
europepmc +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The Serum Level of IL-31 in Patients with Chronic Kidney Disease-Associated Pruritus: What Can We Expect? [PDF]
Świerczyńska K +5 more
europepmc +1 more source

