Results 251 to 260 of about 1,179,733 (270)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Il VI Congresso speleologico internazionale (Olomouc, 31 agosto-13 settembre 1973)
Bollettino della Società Geografica Italiana, 1973 Ugo Sauro
doaj
IL-31-targeting and other novel drugs in itch
Annals of Allergy, Asthma & ImmunologyPeter Olah, Ulrike Raap, Bernhard Homey
openaire +1 more source
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Analiza ekspresji IL-31 u pacjentów z liszajem płaskim
Przegląd Dermatologiczny, 2015 Welz-Kubiak, Kalina, Reich, Adam
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IL‐31 and IL‐31 receptor alpha in pemphigus: Contributors to more than just itch?
The Journal of Dermatology, 2023AbstractPemphigus is an autoimmune blistering disorder with four major subtypes: pemphigus vulgaris (PV), pemphigus vegetans (PVe), pemphigus foliaceus (PF), and pemphigus herpetiformis (PH). Among them, PF and PH present itching as a clinical feature; however, the mechanisms behind the pruritus are still unclear.
Satoshi Okuno +4 more
openaire +2 more sources
Implication of Increased Serum IL-31 for Primary Biliary Cholangitis
Immunological Investigations, 2020Interleukin-31 (IL-31) has diverse biological functions. Increased IL-31 has been found in some skin and autoimmune diseases. There has been no study reporting the association between IL-31 and primary biliary cholangitis (PBC). This study was designed to determine serum IL-31 level and to explore its diagnostic value for PBC as well as the association
Ning, Mu +4 more
openaire +2 more sources
2012
Come succede in media una volta ogni due anni e mezzo, questo mese ha non una ma due Lune piene, e la seconda per tradizione si chiama “blu”. Ma il colore non c'entra.
openaire +1 more source
Come succede in media una volta ogni due anni e mezzo, questo mese ha non una ma due Lune piene, e la seconda per tradizione si chiama “blu”. Ma il colore non c'entra.
openaire +1 more source
IL-31 et prurit : expérience en dermatologie vétérinaire
Revue Française d'Allergologie, 2017Resume La dermatite atopique de l’homme et celle du chien partagent un profil cytokinique qui inclut les IL-2, 4, 6, 13 et 31 qui utilisent la voie de signalisation JAK-STAT. Chez le chien, la souris et le singe (Macaca fascicularis), l’administration d’IL-31, par voie intradermique, sous-cutanee ou intraveineuse, induit un prurit transitoire.
openaire +1 more source