Results 81 to 90 of about 6,730,703 (222)

Increased expression of the interleukin-36 cytokines in lesions of hidradenitis suppurativa. [PDF]

, 2017
BACKGROUND Hidradenitis suppurativa (HS) is a recalcitrant chronic skin disease with poorly understood immunopathogenic mechanisms. Previous studies reported that the interleukin-36 (IL-36) cytokines [IL-36α, IL-36β, IL-36γ and IL-36 receptor ...
C. Schlapbach, Thomi, R, Schlapbach, Christoph, Hunger, Robert, R. Thomi, R.E. Hunger, M. Kakeda, Kakeda, M, N. Yawalkar, Yawalkar, Nikhil   +9 more
core   +4 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

IL rapporto tra art. 36 Cost. e i CCNL. La prescrizione della retribuzione

, 2017
analisi degli orientamenti dottrinali e giurisprudenziali sull'art.
lorenzo zoppoli
core  

Il trattamento del rischio nell'impairment test secondo lo IAS 36

, 2013
Considerare il rischio ad abbattimento dei flussi o a incremento dei tassi? Sviluppare un’unica proiezione corrispondente allo scenario avente maggiore probabilità di realizzazione o costruire una molteplicità di scenari possibili ponderandoli in modo ...
BAVAGNOLI, Francesco
core   +1 more source

IL-36 and IL-1/IL-17 Drive Immunity to Oral Candidiasis via Parallel Mechanisms

, 2018
Protection against microbial infection by the induction of inflammation is a key function of the IL-1 superfamily, including both classical IL-1 and the new IL-36 cytokine families.
Coleman, Bianca M., Diksha Sihra, Sarah L. Gaffen, Naglik, Julian R.; id_orcid, Stacey, M, Richardson, JP, Gaffen, SL, Gaffen, Sarah L., McGeachy, Mandy J., Sihra, D, Martin Stacey, Richardson, Jonathan P.; id_orcid, Zafar, H, Hepworth, OW, Olivia W. Hepworth, Verma, Akash H., Aggor, FEY, Ponde, NO, Felix E. Y. Aggor, Julian R. Naglik, Zafar, Hanna, Stacey, Martin, Jemima Ho, Hepworth, Olivia W., Hube, B, Ho, J, Aggor, Felix E. Y., Joseph S. Ainscough, Coleman, BM, Akash H. Verma, Jonathan P. Richardson, Moyes, DL, Hanna Zafar, Moyes, Dave; id_orcid, Ainscough, Joseph S., Bianca M. Coleman, David L. Moyes, Verma, AH, Ponde, Nicole O., Bernhard Hube, McGeachy, MJ, Nicole O. Ponde, Hube, Bernhard, Sihra, Diksha, Naglik, JR, Mandy J. McGeachy, Ainscough, JS, Ho, Jemima   +47 more
core   +1 more source

IL-27 regulates IL-18 binding protein in skin resident cells [PDF]

, 2012
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and chronic eczema. An imbalance between IL-18 and its endogenous antagonist IL-18 binding protein (BP) may account for increased ...
Wittmann, M, Miriam Wittmann, Werfel, Thomas, Bachmann, M, Doble, Rosella, Muehl, H, Thomas Werfel, Doble Rosella, Pfeilschifter, Josef (Prof. Dr.), Doble, R, Heiko Mühl, Mühl Heiko, Malte Bachmann, Wittmann Miriam, Pfeilschifter, J, Wittmann, Miriam, Bachmann Malte, Werfel, T, Josef Pfeilschifter, Werfel Thomas, Bachmann, Malte, Mühl, Heiko, Rosella Doble, Pfeilschifter Josef   +23 more
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Biology of IL-36 cytokines and their role in disease.

, 2013
Item does not contain fulltextIL-36alpha, IL-36beta, IL-36gamma, and IL-36Ra, collectively called IL-36 cytokines, are part of the IL-1 family. IL-36alpha, IL-36beta, and IL-36gamma are IL-36 receptor (IL-36R) agonists, while IL-36Ra is a receptor ...
Mark S. Gresnigt, Veerdonk, F.L. van de, Gresnigt, M.S., Frank L. van de Veerdonk   +3 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source