Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation [PDF]
Respiratory Research, 2011 Background While the presence of the chitinase-like molecule YKL40 has been reported in COPD and asthma, its relevance to inflammatory processes elicited by cigarette smoke and common environmental allergens, such as house dust mite (HDM), is not well ...
Coyle Anthony J +6 more
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IL-39 increases ROS production and promotes the phosphorylation of p38 MAPK in the apoptotic cardiomyocytes [PDF]
Folia Histochemica et Cytobiologica, 2021 INTRODUCTION: The cytokine interleukin (IL)-39 is a novel member of the IL-12 family. Our previous study found that the serum level of IL-39 significantly increased in patients with acute myocardial infarction. However, the role of IL-39 in cardiomyocyte
Wei Xiong +8 more
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Evaluation of IL-23p19/Ebi3 (IL-39) gingival crevicular fluid levels in periodontal health, gingivitis, and periodontitis. [PDF]
Clin Oral Investig, 2022 OBJECTIVES: IL-23p19/Ebi3 (IL-39) was described as a new IL-12 family member. The aim of this study is to evaluate the gingival crevicular fluid (GCF) IL-39 levels in periodontal diseases and health and to correlate them to GCF levels of IL-1β and ...
Sari A, Dogan S, Nibali L, Koseoglu S.
europepmc +2 more sources
The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man. [PDF]
Inflamm Res, 2019 Objective: The heterodimeric IL-12 family member cytokines including, IL-12, IL-23, IL-27, and IL-35 and have multiple roles in regulating innate and adaptive immunity with crucial functions in inflammatory disorders such as psoriasis.
Bridgewood C +5 more
europepmc +2 more sources
IL-6/IL-12 Cytokine Receptor Shuffling of Extra- and Intracellular Domains Reveals Canonical STAT Activation via Synthetic IL-35 and IL-39 Signaling. [PDF]
Sci Rep, 2017 IL-35 and IL-39 are recently discovered shared members of the IL-6- and IL-12–type cytokine family with immune-suppressive capacity. IL-35 has been reported to induce the formation of four different receptor complexes: gp130:IL-12β2, gp130:gp130, IL-12β2:
Floss DM +7 more
europepmc +2 more sources
Ikaite in the methane anomaly zone on the continental slope of the sea of Japan
Вестник Камчатской региональной ассоциации "Учебно-научный центр". Серия: Науки о Земле, 2020 The results of a study of authigenic carbonate nodules found in bottom sediments on the south-western continental slope of Peter the Great Bay, Sea of Japan, are presented.
Шакиров Р.Б. +7 more
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Endocrinology, Diabetes & Metabolism, 2023 Introduction It is suggested that cytokines play a key role in the pathogenesis of type 2 diabetes mellitus (T2DM). Therefore, this study explored two recently discovered cytokines, interleukin (IL)‐37 (anti‐inflammatory) and IL‐39 (pro‐inflammatory), in
Shahad W. Nussrat, Ali H. Ad'hiah
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Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]
, 2013 Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Heiko Mühl, Heiko eMühl, Mühl, Heiko
core +1 more source
, 2023 Brucellosis is significantly influenced by the interactions between the causative Brucella bacteria and host immunity. Recently identified cytokines have been described for their immunomodulatory effects in numerous inflammatory, autoimmune and ...
Demir, Nesrin +8 more
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The role of the chitinase-like protein BRP-39 in allergic asthma [PDF]
, 2009 Diese Studien zeigen, dass das Chitinase-ähnliche Protein BRP-39 eine entscheidende Rolle in der Pathogenese einer Th2 Entzündung in der Lunge spielt.
Koller, Barbara
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