Results 1 to 10 of about 3,328 (148)

Association between IL-35 Gene Single Nucleotide Polymorphisms and Systemic Lupus Erythematosus in Egypt [PDF]

open access: yesAl-Azhar International Medical Journal, 2022
Background: Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease characterised by a reduced immune tolerance of the body's immune system and an enormous production of autoantibodies, which ultimately cause damage to most of body ...
Hasan Awaad   +3 more
doaj   +1 more source

Evaluation of Some New Cytokines in Rheumatoid Arthritis

open access: yesمجلة كلية الطب, 2022
Background: Cytokines have an essential contribution to the inflammatory response and the development of chronic inflammation. Therefore, it has a pivotal role in the pathogenesis of rheumatoid arthritis (RA). Interleukins are closely related to RA, and
Zahra'a A. Ahmed
doaj   +1 more source

Regulatory B Cells Dysregulated T Cell Function in an IL-35-Dependent Way in Patients With Chronic Hepatitis B

open access: yesFrontiers in Immunology, 2021
Interleukin (IL)-35-secreting B (IL-35+B) cells are critical regulators in autoimmune and infectious diseases and exert suppressive functions in parallel with IL-10-producing B (B10) cells.
YaYun Liu   +6 more
doaj   +1 more source

Elevated IL-35 level and iTr35 subset increase the bacterial burden and lung lesions in Mycobacterium tuberculosis-infected mice

open access: yesOpen Life Sciences, 2022
This study aimed to investigate the relationship between interleukin (IL)-35 level and IL-35-producing regulatory T cells (iTr35 subset) in Mycobacterium tuberculosis (Mtb)-infected mice.
Yu Fangliu   +7 more
doaj   +1 more source

TB and COVID-19: An Exploration of the Characteristics and Resulting Complications of Co-infection

open access: yesFrontiers in Bioscience-Scholar, 2022
Tuberculosis (TB) and Coronavirus Disease-19 (COVID-19) infection are two respiratory diseases that are of particular concern epidemiologically. Tuberculosis is one of the oldest diseases recorded in the history of mankind dating back thousands of years.
Erica Luke   +3 more
doaj   +1 more source

The diagnostic value of interleukin 35 as a septic biomarker: A meta-analysis

open access: yesFrontiers in Medicine, 2022
BackgroundThere is growing evidence that interleukin 35 (IL-35) represents a potential diagnostic biomarker for sepsis. The purpose of this meta-analysis was to evaluate the overall diagnostic accuracy of IL-35 in sepsis.Materials and methodsFrom October
Yuanhui Hu, Dongling Tang, Pingan Zhang
doaj   +1 more source

Expanding Diversity in Molecular Structures and Functions of the IL-6/IL-12 Heterodimeric Cytokine Family

open access: yesFrontiers in Immunology, 2016
The interleukin (IL)-6/IL-12 family cytokines have pleiotropic functions and play critical roles in multiple immune responses. This cytokine family has very unique characteristics in that they are composed of two distinct subunits forming a heterodimer ...
Hideaki Hasegawa   +5 more
doaj   +1 more source

Differences in Perceived Stress and Depression among Weight (Dis)Satisfied Midwestern College Students during COVID-19

open access: yesCOVID, 2023
Background: Stress and depression are common mental health concerns among college students. Factors related to weight status and stigma are associated with poor mental health outcomes.
Cedric Harville, Ellen Santos
doaj   +1 more source

Effect of antidiabetic therapy on TNF-α, IL-18, IL-23 and IL-35 levels in T2DM patients with coincidental Helicobacter pylori infection

open access: yesJournal of Taibah University for Science, 2020
This study aimed to evaluate the relationship between tumour-necrosis factor-alpha (TNF-α), interleukin (IL)-18, IL-23, IL-35 and Heilcobacter (H) pylori infection with T2DM. A total of 25 healthy subjects and 102 confirmed T2DM patients were enrolled in
Adel Abdel-Moneim   +3 more
doaj   +1 more source

Increased P-35, EBI3 Transcripts and Other Treg Markers in Peripheral Blood Mononuclear Cells of Breast Cancer Patients with Different clinical Stages [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Purpose: Currently, cancer as a major problem around the world threatens human health and has a high incidence in developing countries. Many reports have indicated that patients suffering from cancer demonstrate decreased antitumor immune responses as ...
Maryam Hamidinia   +6 more
doaj   +1 more source

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