Results 1 to 10 of about 399,292 (120)

The diagnostic value of interleukin 35 as a septic biomarker: A meta-analysis

Frontiers in Medicine, 2022
BackgroundThere is growing evidence that interleukin 35 (IL-35) represents a potential diagnostic biomarker for sepsis. The purpose of this meta-analysis was to evaluate the overall diagnostic accuracy of IL-35 in sepsis.Materials and methodsFrom October
Yuanhui Hu, Dongling Tang, Pingan Zhang
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Regulatory B Cells Dysregulated T Cell Function in an IL-35-Dependent Way in Patients With Chronic Hepatitis B

Frontiers in Immunology, 2021
Interleukin (IL)-35-secreting B (IL-35+B) cells are critical regulators in autoimmune and infectious diseases and exert suppressive functions in parallel with IL-10-producing B (B10) cells.
YaYun Liu, Ying Luo, Tong Zhu, Meng Jiang, ZhaoFeng Tian, GuSheng Tang, XueSong Liang   +6 more
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Pancreatic cancer: Emerging field of regulatory B-cell-targeted immunotherapies

Frontiers in Immunology, 2023
Pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, is characterized by a high mortality rate and poor prognosis.
Zeynep Nur Senturk, Isilay Akdag, Bahar Deniz, Ayca Sayi-Yazgan   +3 more
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Interleukin 35: protective role and mechanism in type 1 diabetes

Central European Journal of Immunology, 2023
Interleukin 35 (IL-35), a cytokine secreted by regulatory T (Treg) cells from the differentiation of conventional CD4+ T cells, is a member of the IL-12 family. The IL-12 family of cytokines exhibits an anti-inflammatory property. IL-35 has recently been
Si-Ming Zhang, Jun Liang, Ji-Ping Xia, Li Li, Li Zheng, Ya-Lan Wang, Yan-Hong Li, Yan Li, Yu Lu   +8 more
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Recombinant p35 from bacteria can form Interleukin (IL-)12, but Not IL-35. [PDF]

PLoS ONE, 2014
The Interleukin (IL)-12 family contains several heterodimeric composite cytokines which share subunits among each other. IL-12 consists of the subunits p40 (shared with IL-23) and p35.
Samadhi Aparicio-Siegmund, Jens M Moll, Juliane Lokau, Melanie Grusdat, Jutta Schröder, Svenja Plöhn, Stefan Rose-John, Joachim Grötzinger, Philipp A Lang, Jürgen Scheller, Christoph Garbers   +10 more
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Interleukin-35 inhibited the production of histamine and pro-inflammatory cytokines through suppression MAPKs pathway in HMC-1 cells

Allergy, Asthma & Clinical Immunology, 2021
Background IL-35 is a newly anti-inflammatory cytokine that belongs to the IL-12 family. Mast cells, as one of the major effector cells in the immune response system, plays an important role in the pathogenesis of chronic spontaneous urticarial (CSU ...
Li-xin Fu, Tao Chen, Qiao-mei Sun, Pei-mei Zhou, Zai-pei Guo   +4 more
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Pathogenesis and Function of Interleukin-35 in Rheumatoid Arthritis

Frontiers in Pharmacology, 2021
It is well known that RA (Rheumatoid arthritis) is an autoimmune disease characterized by multiple and symmetric arthropathy. The main pathological features of RA are synovial hyperplasia, angiogenesis, pannus formation, inflammatory cell infiltration ...
Pan Lin Xin, Li Fan Jie, Qian Cheng, Du Yi Bin, Cheng Wen Dan   +4 more
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Inducible nitric oxide synthase-expressing myeloid-derived suppressor cells regulated by interleukin 35 contribute to the pathogenesis of psoriasis

Frontiers in Immunology, 2023
Although psoriasis is classified as a T cell-mediated inflammatory disease, the contribution of myeloid cells to the pathogenesis of psoriasis is not fully understood.
Junfeng Zhang, Junfeng Zhang, Yunsheng Zhang, Zhiya Yang, Dalei Cheng, Hui Zhang, Hui Zhang, Li Wei, Chen Liu, Fenglian Yan, Fenglian Yan, Chunxia Li, Chunxia Li, Guanjun Dong, Guanjun Dong, Changying Wang, Changying Wang, Dongmei Shi, Huabao Xiong   +18 more
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Interleukin-35 Expression in Non-Small Cell Lung Cancer is Associated with Tumor Progression

Cellular Physiology and Biochemistry, 2018
Background/Aims: Lung cancer continues to be the leading cause of cancer related deaths worldwide due to its high incidence, malignant behavior and lack of major advancements in treatment strategy. The occurrence and development of lung cancer is closely
Mingfei Sun, Xianjie Zheng, Qingjiang Meng, Yanjun Dong, Guoyu Zhang, Dexin Rao, Xiaokang An, Zhongxin Yang, Lihong Pan, Shuanglin Zhang   +9 more
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Association of three single nucleotide polymorphisms of interleukin -35 for detection and prediction of women with breast cancer in Erbil city

Zanco Journal of Pure and Applied Sciences, 2022
Background: Interleukins have a substantial role in the improvement of many types of cancer. Interleukin genes have many single nucleotide polymorphisms (SNPs) that may alter protein synthesis or function, and many of them have been related to cancer ...
Zhian Ismael A. Daham, Suhaila N. Darogha   +1 more
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