Results 11 to 20 of about 59,730,718 (209)
Mathematical modeling of Interleukin-35 promoting tumor growth and angiogenesis.
PLoS ONE, 2014 Interleukin-35 (IL-35), a cytokine from the Interleukin-12 cytokine family, has been considered as an anti-inflammatory cytokine which promotes tumor progression and tumor immune evasion. It has also been demonstrated that IL-35 is secreted by regulatory
Kang-Ling Liao +2 more
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Current Research of the Roles of IL-35 in Tumor Progression
Chinese Journal of Lung Cancer, 2016 Interleukin(IL)-35 is a new member of the interleukin-12 superfamily. Since its first report in 2007, IL-35 rapidly became a research highlight in the field of immunology.
Chongbiao HUANG +6 more
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Interleukin-35 pathobiology in periodontal disease: a systematic scoping review [PDF]
BMC Oral Health, 2021 Background Interleukin (IL)-35 is a novel anti-inflammatory cytokine that is produced by regulatory T cells. IL-35 mediates immunological functions and plays a protective role in several diseases such as asthma and rheumatoid arthritis. However, the role
Patrick R. Schmidlin +2 more
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Interleukin-35 on B cell and T cell induction and regulation
Journal of Inflammation, 2017 Interleukin (IL)-35 is a relatively newly discovered member of IL-12 cytokine family that is unique in that it is a dimer formed by two subunits. The review documents the structure, secretion and signal transduction of IL-35, the regulation effect of IL ...
Ai Huang +5 more
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Effect of interleukin (IL)-35 on IL-17 expression and production by human CD4+ T cells [PDF]
PeerJ, 2017 Background Interleukin (IL)-17 produced by mainly T helper 17 (Th17) cells may play an important destructive role in chronic periodontitis (CP). Thus, anti-inflammatory cytokines, such as IL-35, might have a beneficial effect in periodontitis by ...
Kosuke Okada +12 more
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Rapid Communication: Plasma Interleukin-35 in Children with Autism [PDF]
Brain Sciences, 2019 In autism spectrum disorders (ASD) many individuals have co-morbid immune dysregulation that can lead to inflammation in the brain and periphery. The novel cytokine interleukin (IL)-35 has described anti-inflammatory properties; however, the plasma ...
Destanie Rose, Paul Ashwood
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Role of interlekin-35 as a biomarker in patients with newly diagnosed Hashimoto’s thyroiditis
Endocrine Regulations, 2016 Objective. Interleukin-35 (IL-35), an interleukin-12 (IL-12) cytokine family member, is shown to be a potent immunosuppressive and anti-inflammatory cytokine. Inducible regulatory T cells (Tregs) produce IL-35 that mediates the immune inhibitory function
Yilmaz Hakki +4 more
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Reduced circulating interleukin 35 is associated with enhanced peripheral T cell function in primary biliary cholangitis [PDF]
Biomolecules & Biomedicine, 2023 Interleukin 35 (IL-35) mediates immunosuppression of T cells in autoimmune diseases. T cells play an important role in primary biliary cholangitis (PBC) with incompletely elucidated pathogenesis. Thus, we aimed to investigate the role of IL-35 regulation
Siqi Liu +6 more
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Expression and significance of IL-27 and IL-35 in orbital fat in patients with severe TAO
Diagnostic PathologyTo detect the expression of Interleukin-27 (IL-27) and Interleukin-35 (IL-35) in orbital fat in patients with severe TAO (thyroid-related eye disease) exophthalmos, and to investigate its potential role and significance in the development of TAO. A study
Bing Wang +4 more
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Arthritis Research & TherapyObjective This study aimed to explore the role of interleukin-35 (IL-35)-mediated regulatory B cells (Bregs) in modulating inflammation and fibrosis in systemic sclerosis (SSc).
Wen Zeng +8 more
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