Results 21 to 30 of about 55,844,280 (246)

Evaluation of Serum IL-39 Levels in Patients with Polycystic Ovary Syndrome. [PDF]

J Clin Med
Background/Objectives: Polycystic ovary syndrome (PCOS) is a common endocrine disorder associated with chronic low-grade inflammation. Interleukin-39 (IL-39), a newly identified cytokine, has been implicated in immune regulation; however, its role in PCOS remains unclear.
Kagitci M, Bahceci I, Kivrak M, Deseet SA, Senturk S.   +4 more
europepmc   +2 more sources

A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice. [PDF]

Eur J Immunol, 2016
Interleukin‐12 family cytokines have emerged as critical regulators of immunity with some members (IL‐12, IL‐23) associated with disease pathogenesis while others (IL‐27, IL‐35) mitigate autoimmune diseases. Each IL‐12 family member is comprised of an α and a β chain, and chain‐sharing is a key feature.
Wang X, Wei Y, Xiao H, Liu X, Zhang Y, Han G, Chen G, Hou C, Ma N, Shen B, Li Y, Egwuagu CE, Wang R.   +12 more
europepmc   +4 more sources

Correction to: The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man. [PDF]

Inflamm Res, 2019
The original article can be found online.
Bridgewood C, Alase A, Watad A, Wittmann M, Cuthbert R, McGonagle D.   +5 more
europepmc   +6 more sources

IL-39 and IL-35 gingival crevicular fluid levels in diabetic patients with generalized periodontitis. [PDF]

Clin Oral Investig
Abstract Objectives This research was performed to investigate if there is a role for IL-39 in immunopathogenesis of both systemically healthy and diabetic periodontitis patients. Additionally, to explore if we can consider IL-39 and IL-35 as biomarkers for periodontitis activity. Materials
Hassan SS, Abdelkawy M, Shaker OG, Tarrad NAF.   +3 more
europepmc   +3 more sources

Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice. [PDF]

Mol Med Rep, 2018
The interleukin (IL)‑12 family cytokines have been examined as therapeutic targets in the treatment of several autoimmune diseases. Our previous study showed that a novel IL‑12 family cytokine, IL‑39 (IL‑23p19/Ebi3) mediates inflammation in lupus‑like mice.
Wang X, Zhang Y, Wang Z, Liu X, Zhu G, Han G, Chen G, Hou C, Wang T, Shen B, Li Y, Xiao H, Ma N, Wang R.   +13 more
europepmc   +4 more sources

IL-39 Reduces Proliferation and Promotes Apoptosis of Bladder Cancer by Altering the Activity of Cyclin E and Fas [PDF]

Anticancer Research, 2021
This study was designed to investigate the effect of IL-39 on T24 bladder cancer (BC) cell line survival and growth.In order to assess the direct effect of IL-39 on survival, proliferation, and apoptosis of T24 BC cells, we utilized a clonogenic survival assay, a cell proliferation assay, and caspase-3 activity kits.
Huaping, Xiao, Hamza, Alisic, Brandon T, Reiman, Zuliang, Deng, Ziwen, Zhu, Nathan T, Givens, Qian, Bai, Andrew, Tait, Mark R, Wakefield, Yujiang, Fang   +9 more
openaire   +2 more sources

Correction to: IL-39 acts as a friend to pancreatic cancer [PDF]

Medical Oncology, 2019
The original version of this article unfortunately contained a mistake in the text of the entire article. The word "IL-39" should read as "meteorin-like protein". This has been corrected with this correction.
Alicia A. Manning, Lei Zhao, Ziwen Zhu, Huaping Xiao, Chase G. Redington, Vivi A. Ding, Theodore Stewart-Hester, Qian Bai, Jacob Dunlap, Mark R. Wakefield, Yujiang Fang   +10 more
openaire   +2 more sources

Interleukin −39 Expression in Pleural Effusion and Its Diagnostic Value for Tuberculous Pleurisy

Journal of Inflammation Research
Xuxiang Song,1,2,* Qipan Zhang,3,* Tiantian Cen,1,3,* Wei Fan,1,2 Weili Chen,1,2 Lun Guo,4 Yingying Du,1,2 Chengna Lv,2 Pan Tang,2 Zhaoxing Dong,5 Mingcai Li,6 Qunli Ding2 1Health Science Center, Ningbo University, Ningbo, People’s Republic ...
Song X, Zhang Q, Cen T, Fan W, Chen W, Guo L, Du Y, Lv C, Tang P, Dong Z, Li M, Ding Q   +11 more
doaj   +1 more source

Salivary asprosin, IL-39, IL-40, and IL-1β levels in diabetic patients with periodontitis: A cross-sectional analysis. [PDF]

Clin Oral Investig
Abstract Objective Periodontitis and type 2 diabetes mellitus (T2DM) are chronic diseases with a well-established bidirectional relationship. Recent studies have focused on salivary biomarkers to better understand their shared inflammatory mechanisms.
Oruc AH, Babayiğit O.
europepmc   +3 more sources

A novel Link of Serum IL-39 Levels in Patients with Rheumatoid Arthritis

Iraqi Journal of Science, 2023
      Rheumatoid arthritis (RA) is an inflammatory condition causing joint pain and stiffness, with often debilitating and life-limiting consequences. Recently, a new B-cell secreted cytokine, IL-39, was identified in mice. The most up-to-date research indicates that although IL-39 is expressed in murine models of lupus and has a role in mediating the ...
Zahraa Adnan Ghadhban Al Ghuraibawi, Inas K. Sharquie, Faiq I. Gorial   +2 more
openaire   +1 more source