Results 101 to 110 of about 1,458,458 (304)

C‐Terminal Nucleobase Modification Amplifies Peptide‐Mediated Liposome Fusion

open access: yesChemistry – A European Journal, EarlyView.
Let's come together right now. Cationic peptides are known to promote aggregation of negatively charged liposomes through electrostatic interaction. The process is reversible: once neutrality is achieved, liposomes disaggregate. Here, we demonstrate that end‐capping peptides with nucleobases turns the process into irreversible fusion.
Laura Morbiato   +4 more
wiley   +1 more source

DirectProfil : de la navigation au partage de documents hypermedia

open access: yes, 1999
International audienceIn this article, authors describe an help concept about web hypertext surfing and value-added information sharing. Moderns needs in ability to manipulate recent information and communication Tools driven by technologic abrupt ...
Dou Goarin, Carine, Giraud, Eric
core   +1 more source

Chemical Ligation of Backbone N‐hydroxylated Peptides

open access: yesChemistry – A European Journal, EarlyView.
Peptide backbone N‐hydroxylation enables sequence‐agnostic fragment ligation via hydroxamate O‐acyl capture and O→N acyl transfer in water. Broad tolerance of sterically demanding nucleophilic residues is observed, and reductive N─O cleavage restores the native amide bond.
Natalia Cano‐Sampaio   +1 more
wiley   +1 more source

Bright Solvatochromic Fluorophores With Dual Emission Enabled by a Donor‐Engineering Strategy

open access: yesChemistry – A European Journal, EarlyView.
We screened tertiary amines for installation on the donor unit of highly emissive donor–acceptor‐type solvatochromic fluorophores based on a 9,9‐dimethyl‐2‐phenyl‐9H‐fluorene scaffold, with the aim of enabling two bright emissive states to coexist. As a result, the azetidine derivative [4] and the azepane derivative [7] exhibited clear dual emission ...
Kensei Konishi, Gen‐ichi Konishi
wiley   +1 more source

Establishing Interventional Radiology in a Low-Resource Setting: Lessons From Obafemi Awolowo University Teaching Hospitals Complex, Nigeria

open access: yesJCO Global Oncology
PURPOSEThe introduction of an interventional radiology (IR) unit at the Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC) in 2017 marked a significant advancement in health care delivery in a low-resource setting in Nigeria.
Adeleye D. Omisore   +17 more
doaj   +1 more source

Internal localized eigenmodes on spin discrete breathers in antiferromagnetic chains with on-site easy axis anisotropy

open access: yes, 2002
We investigate internal localized eigenmodes of the linearized equation around spin discrete breathers in 1D antiferromagnets with on-site easy axis anisotropy.
A.J. Sievers   +16 more
core   +1 more source

Isotopic and genetic methods reveal the role of the gut microbiome in mammalian host essential amino acid metabolism. [PDF]

open access: yes, 2020
Intestinal microbiota perform many functions for their host, but among the most important is their role in metabolism, especially the conversion of recalcitrant biomass that the host is unable to digest into bioavailable compounds.
Bradley, Christina J   +5 more
core   +1 more source

Total Syntheses of Agelamadin F and (±)‐Tauroacidin A, Enabled by NaClO2‐Mediated Coupling Reactions of Oroidin and Amines

open access: yesChemistry – A European Journal, EarlyView.
Total syntheses of agelamadin F and (±)‐tauroacidin A were achieved by sodium chlorite (NaClO2)‐mediated oxidative C─N coupling. Nine C15–N–amino acid‐substituted oroidin derivatives were successfully prepared to demonstrate the applicability and versatility of this oxidative coupling reaction.
Ryosuke Hirozumi   +3 more
wiley   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

open access: yesCytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

A Profile of Medicaid Managed Care Programs in 2010: Findings From a 50-State Survey [PDF]

open access: yes, 2011
Examines types of Medicaid managed care organizations and contracts by state, including managed care organizations and primary care case management programs; issues for measuring, monitoring, and improving quality; and implications of health ...
Dyke Snipes   +3 more
core  

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